Thyrotoxic Periodic Paralysis Clinical Trial
Official title:
Genetic Analysis of Thai Patients With Thyrotoxic Periodic Paralysis
Verified date | March 2007 |
Source | Ramathibodi Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | Thailand: Ethical Committee |
Study type | Observational |
Thyrotoxic periodic paralysis (TPP) is characterized by episodes of reversible hypokalemia and weakness in thyrotoxic patients. It is commonly found in males of Asian descent and is also seen in individuals having Native American or Hispanic ancestry. Therefore genetic etiology has been hypothesized. This study, we aim to find the susceptibility genes that associate with TPP. Both candidate genes approach and genome wide association study have been conducted.
Status | Completed |
Enrollment | 80 |
Est. completion date | December 2005 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Male |
Age group | 15 Years and older |
Eligibility |
Inclusion Criteria: TPP - Hyperthyroid patients from any causes - Evidence of hypokalemia (k<3.5 mg/dl)from intracellular shift (Urine K<15 mg/dl, TTKG<2) - Episodic paralysis Exclusion Criteria: - Hypokalemia from GI or renal loss |
Observational Model: Case Control, Primary Purpose: Screening, Time Perspective: Cross-Sectional
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Ramathibodi Hospital |
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT02287363 -
Genetic and Morphological Analysis of Thyrotoxic Periodic Paralysis
|
N/A |