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PheWAS of a Polygenic Predictor of Thyroid Function — PHETHYR  

Thyroid Clinical Trial

Official title:
PheWAS of a Polygenic Predictor of Thyroid Function

Clinical Trial Summary

Performing a phenome-wide association study (PheWAS) identifying clinical diagnoses associated with a polygenic predictor of Thyroid stimulating hormone (TSH) levels identified by a previously published genome-wide association study (GWAS). PheWAS will be applied in an electronic-health-record (EHR) cohort including North American (n: 37,154) and European participants using 1,318 phenotypes.

Clinical Trial Description

Applying a genetic predictor of thyroid stimulating hormone levels to an electronic-health-record cohort to verify associations with thyroid disorders as positive controls, and identify new associations . ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03597659
Study type Observational
Source Groupe Hospitalier Pitie-Salpetriere
Contact
Status Completed
Phase
Start date September 1, 2017
Completion date July 1, 2018
View Details
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