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Thyroid Nodule clinical trials

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NCT ID: NCT04680650 Active, not recruiting - Thyroid Nodule Clinical Trials

Comparison of Anesthesia Effects of Sevoflurane and Propofol Combined With Dexmedetomidine in Intraoperative Neuromonitoring During Thyroidectomy

Start date: April 30, 2020
Phase: N/A
Study type: Interventional

According to the previous studies, it is reported that the use of sevoflurane in the maintenance of anesthesia may lead to delayed occurrence of positive electromyographic (EMG) signal and lower obtained signal amplitude. In this study, the investigators aimed to investigate the anesthetic effect of sevoflurane combined with dexmedetomidine for neuromonitoring during thyroid surgery. The investigators hypothesize that sevoflurane combined with dexmedetomidine can reduce the movement or spontaneous activity of vocal cords in patients and without affecting the EMG signals.

NCT ID: NCT04046354 Active, not recruiting - Ablation Clinical Trials

Microwave vs. Radiofrequency Ablation for Benign Thyroid Nodules: A Multicenter Randomized Controlled Trial Study

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

Compared with traditional treatment methods, ultrasound-guided thermal ablation is more targeted, less invasive and more reliable. The study compared microwave ablation and radiofrequency ablation to evaluate the efficacy and safety in the treatment of benign thyroid nodules with a multicenter data, which will provide a basis for clinical treatment.

NCT ID: NCT02953288 Active, not recruiting - Thyroid Cancer Clinical Trials

Differential Diagnosis and Clinical Treatment Strategies of Thyroid Nodules.

Start date: October 2016
Phase: N/A
Study type: Observational

To investigate the genetic mutations of patients with thyroid carcinoma and find molecular targets for therapy.

NCT ID: NCT02714946 Active, not recruiting - Thyroid Nodule Clinical Trials

Laser Ablation Versus Radiofrequency Ablation for Thyroid Nodules

LARA
Start date: January 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to prospectively compare percutaneous radiofrequency ablation (RFA) versus percutaneous laser ablation (LA) for the treatment of solid thyroid nodules.

NCT ID: NCT02681328 Active, not recruiting - Thyroid Clinical Trials

Randomized Trial Comparing Performance of Molecular Markers for Indeterminate Thyroid Nodules

Start date: May 1, 2016
Phase:
Study type: Observational

The purpose of this study is to compare the performance of Afirma GSC and ThyroSeq v.3 in indeterminate thyroid nodules to determine which test can allow more patients to avoid unnecessary surgery and preserve quality of life. In the initial phase of this study, the performance of Afirma GEC and ThyroSeq v.2 were compared.

NCT ID: NCT01756534 Active, not recruiting - Thyroid Nodule Clinical Trials

Oxidized Cellulose Hemostatic Agent in Thyroid Surgery: a Prospective Randomized Controlled Study

Start date: January 2011
Phase: N/A
Study type: Interventional

This single-blind prospective randomized study was designed to assess the efficacy and safety of the use of Surgicel® compared to the use of conventional surgical procedures (ligatures and bipolar electrocautery alone) to achieve hemostasis in thyroid surgery

NCT ID: NCT00150150 Active, not recruiting - Clinical trials for Cystic Thyroid Nodules

Laser Therapy of Benign Thyroid Nodules

Start date: January 2001
Phase: Phase 3
Study type: Interventional

Nodular goitre is common in the general population and less than 5% of the patients who undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion. Nodules left untreated seem to have a slight growth potential in borderline iodine-deficient areas. Interstitial laser photo-coagulation (ILP) is a procedure for local hyperthermia and photocoagulation, allowing minimally invasive treatment of benign tumors, including thyroid nodules. The aim of these studies are to evaluate if ILP will be useful in reducing the volume of the benign thyroid nodule and thyroid function will be unaffected in euthyroid patients, and normalized in pretoxic- and toxic thyroid nodules. The investigations are listed below: 1. Randomized study of interstitial laser photocoagulation for benign solitary cold thyroid nodules – one versus two or three treatments 2. Randomized study of interstitial laser photocoagulation for benign solitary autonomous thyroid nodules – 131I versus laser ablation 3. Interstitial laser photocoagulation for benign thyroid cystadenomas. – a feasibility study.