Effect of Intravenous Magnesium on Postoperative Sore Throat After Thyroidectomy

Thyroid Neoplasms Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02826746
• Other study ID #: AJIRB-MED-CT4-16-089
• Status: Completed
• Phase: N/A
• Start date: July 2016
• Est. completion date: March 2019

Study information

• Verified date: April 2019
• Source: Ajou University School of Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The primary purpose of this study is to investigate the effect of intravenous magnesium on postoperative throat pain after thyroidectomy.

The secondary purpose of this study is to investigate the effect of intravenous magnesium on total dose of fentanyl in recovery room after thyroidectomy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: March 2019
• Est. primary completion date: March 2019
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years to 85 Years

Eligibility

Inclusion Criteria:

• Thyroidectomy

Exclusion Criteria:

• Allergy to magnesium

• Chronic pain

• Chronic opioid use

• Chronic NSAID use

• Renal dysfunction

• Liver dysfunction

• Cardiac arrythmia

• Seizure

Related Conditions & MeSH terms

• Thyroid Neoplasms

Intervention

Drug:
• Magnesium Sulfate
adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h
• Normal saline
the same bolus and infusion volumes of normal saline

Locations

Country	Name	City	State
Korea, Republic of	Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine	Suwon	Seoum

Sponsors (1)

Lead Sponsor	Collaborator
Ajou University School of Medicine

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Throat pain	pain assessment using visual analog scale	Up to 48 hours after surgery end
Secondary	Fentanyl dose in recovery room		Up to 30 minutes after surgery end