Frequency of Florid Hyperthyroidism In Patients Taking Iodinated Salt

Thyroid Dysfunction Clinical Trial

— I2 and thyroid  

Official title:

Frequency of Florid Hyperthyroidism In Patients Taking Iodinated Salt: A Cross Sectional Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04809454
• Other study ID #: 1241985
• Status: Not yet recruiting
• Start date: October 2021
• Est. completion date: March 2022

Study information

• Verified date: September 2021
• Source: Services Institute of Medical Sciences, Pakistan
• Contact: Mehwish Iftikhar, FCPS Endocrinologyy
• Phone: 923004291641
• Email: drmehwish19[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Thyroxin a vital hormone for life lot of body functions depend on proper functioning on pituitary thyroid axis. it exists in two major forms Thyroxine (T4) and (T3) , each of them containing two iodine atoms on their inner (tyrosine) ring. Synthesis of reasonable quantities of thyroid hormones requires adequate iodine intake to allow sufficient thyroidal uptake. The World Health Organization (WHO) recommendation for daily intake of iodine is 150 μg for children ≥12 years and adults, and 250 μg for pregnant and lactating women. However as we know optimum amount of iodine is required for normal pituitary thyroid axis like wise excessive intake may cause over functioning of axis hence over production of hormone that can be manifested both clinically and biochemically.

This study is designed to observe the frequency of over hyperthyroidism in patients taking iodinated salt.

Description:

All patients presenting to endocrine clinic fulfilling inclusion and exclusion criteria will be recruited. They will be examined, their vitals including blood pressure pulse will be noted, thyroid clinical examination including eye signs and thyroid status will be done biochemical Thyroid profile (TSH, Free T3 & Free T4) will be noted in predesigned proforma.

Statistical Analysis will be done ,after data is entered in Statistical Package for the Social Sciences (SPSS) version 25 .qualitative data will be presented as frequencies and percentages while quantitative data will be presented as mean medians and standard deviations.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: March 2022
• Est. primary completion date: March 2022
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

1. All patients presenting with biochemical hyperthyroidism

2. Who are taking Iodinated salt.

3. Treatment naïve patients

4. Both genders included

5. All patients who can give consent (18-60 years)

Exclusion Criteria:

1) Pregnant females 2) Lactating mothers

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Related Conditions & MeSH terms

• Hyperthyroidism
• Thyroid Dysfunction

Locations

Country	Name	City	State
Pakistan	Mehwish Iftikhar	Lahore	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Services Institute of Medical Sciences, Pakistan

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Affect of Iodinated Salt on Thyroid Status	Affect of Iodinated Salt on Thyroid Status	through study completion an average of 12 weeks