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Renal Tracer Elimination in Thyroid Cancer Patients Treated With 131-Iodine — RETENTION  

Thyroid Carcinoma Clinical Trial

Official title:
Relationship Between Estimated Glomerular Filtration Rate and Biological Half-life of 131I. Prospective Analysis in Patients With Differentiated Thyroid Carcinoma.

Clinical Trial Summary

Correlation analysis between estimated renal function and biological half life of 131-I during radioiodine treatment of patients with differentiated thyroid cancer.

Clinical Trial Description

131-I during radioiodine treatment of patients with differentiated thyroid cancer is mainly renally excreted. It is advised in the clinical guidelines that serum creatinine should be determined before applying 131-I and if necessary the administered dose should be reduced. Nevertheless no guideline gives advice in what extent the dose should be decreased. The adjustment is at the discretion of the attending physician. Aim of this prospective study is to correlate the biological half life of 131-I with the renal function to give objective recommendations concerning the reduction of the applied dose in patients with limited renal function. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02773667
Study type Observational
Source Jena University Hospital
Contact
Status Completed
Phase
Start date January 2016
Completion date December 2022
View Details
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