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Platelet Augmentation Using C. Papaya Leaf Extract in Live Donor Liver Transplantation

Thrombocytopenia Clinical Trial

Official title:
Efficacy and Safety of Platelet Augmentation Using Carica Papaya Leaf Extract in Live Donor Liver Transplantation Recipients - a Pilot Randomized Controlled Trial

Clinical Trial Summary

This project is a pilot randomized controlled trial aimed at investigating the potential of Carica Papaya Leaf Extract, available in a marketed pill formulation, in increasing platelet counts in live donor liver transplant recipients. Carica Papaya leaf extract has shown positive results in increasing platelet counts in various medical conditions such as Dengue, Immune thrombocytopenic purpura and chemotherapy induced thrombocytopenia. Thrombocytopenia i.e. low platelet counts are a common occurrence in patients with chronic liver disease undergoing live donor liver transplant. It has been observed in previous studies that live donor liver transplant recipients who have persistent thrombocytopenia have significantly worse outcomes as compared to patients who have higher platelet counts. Positive results in this study lead to further studies in assessing the impact of platelet augmentation in live donor liver transplant recipients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05360134
Study type Interventional
Source Institute of Liver and Biliary Sciences, India
Contact Anubhav Harshit Kumar, MCh
Phone 8860188337
Email anubhav.pawar@gmail.com
Status Recruiting
Phase N/A
Start date January 1, 2021
Completion date December 31, 2022
View Details
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