Clinical Trials Logo

Clinical Trial Summary

to investigate the efficacy and safety of opioid-free anesthesia for non-small-cell lung cancer resection and its underlying clinical value


Clinical Trial Description

Opioids used to have its irreplaceable role in standard opioid-based anesthesia, yet with the help of hypnotics, local anesthetics, anti-inflammatory drugs, α-2 agonists and epidural techniques, opioid-free anesthesia (OFA) has been proved to be safe and feasible for non-cardiac major surgeries. Opioid-sparing anesthesia (OSA) is encouraged by the needs of enhanced recovery and recommended by the latest guidelines for anesthesia of lung surgery. According to previous studies, both opioid-sparing and opioid-free anesthesia would reduce the incidence of opioid-related adverse events and speed up the postoperative recovery to some extent, yet no studies ever are dedicated to compare these two different techniques. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05063396
Study type Interventional
Source Shanghai Zhongshan Hospital
Contact SHUWEI WANG
Phone +8613564440601
Email veronicawang228@126.com
Status Recruiting
Phase N/A
Start date October 1, 2021
Completion date December 1, 2025

See also
  Status Clinical Trial Phase
Recruiting NCT04837950 - Changes in Pleural Cavity Volume and Surgical Exposure N/A
Completed NCT03121287 - Early Imaging Biomarkers in NSCLC
Completed NCT04553471 - Palliative Lattice Stereotactic Body Radiotherapy (SBRT) for Patients With Sarcoma, Thoracic, Abdominal, and Pelvic Cancers N/A
Recruiting NCT05053230 - A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer N/A
Completed NCT04570722 - Ipsilateral Peripheral Intravenous Access Procedures (The iPIVAP Study) N/A
Completed NCT05459311 - Investigating Radiation-Induced Injury to Airways and Pulmonary Vasculature in Lung Stereotactic Ablative Body Radiotherapy (SAbR)
Completed NCT01833637 - Electronic Patient Reported Symptom Assessment N/A
Completed NCT03676426 - Comparison of a Web-based Advance Directive to a Standard Advance Directive N/A
Completed NCT03658083 - Exploring Robotic-assisted Thoracic Surgery for Lung Cancer
Recruiting NCT03804307 - Short Course Radiation Therapy in Palliative Treatment of Thoracic Cancer N/A
Enrolling by invitation NCT05629065 - Pathways to Advance Targeted and Helpful Serious Illness Conversations (PATH-SIC) N/A
Recruiting NCT04749212 - Perioperative Troponin I and NT Pro-BNP in Lung Resection
Recruiting NCT05502263 - Interest of CPET to Predict Mortality and Complications of Lung Resection Candidates
Recruiting NCT05351268 - 3DPCT Combined With CT Guided RISI in the Treatment of Thoracic Malignant Tumors N/A
Recruiting NCT05349552 - Safety and Efficacy of SBRT in the Treatment of Thoracic Malignant Tumors at Different Sites
Recruiting NCT05549414 - Pivotal Study of Proton Radiotherapy Treatments Using Fixed Beam Chair-Based Delivery System N/A
Recruiting NCT06342284 - Patient-Generated Health Data Collection During Chemoradiotherapy for Lung Cancer
Recruiting NCT04799561 - Teleprehabilitation for Surgical Cancer Patients N/A
Completed NCT05143541 - Use of a New Stapling Device in General Thoracic Surgery
Active, not recruiting NCT04686500 - VisionRT-based Deep Inspiration Breath-hold (DIBH) Respiratory Motion Management Strategy, A Pilot Study for Thoracic and Abdominal Tumors N/A