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Terbutaline Adverse Reaction clinical trials

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NCT ID: NCT04468568 Completed - Myelomeningocele Clinical Trials

In Utero Repair of Myelomeningocele: Atosiban Versus Terbutaline

Start date: October 1, 2017
Phase:
Study type: Observational

Myelomeningocele is a malformation with high incidence, and it consists in a neural tube defect. Fetal intrauterine surgery is an alternative for correction, and it improves the prognosis of the fetus, but has an increased risk of maternal complications and premature labor, as it can occur due to uterine stimulation. It is therefore essential that tocolysis is performed before, during and after surgery, and the most commonly used tocolytics are terbutaline and atosiban. Terbutaline has no specificity and may have several adverse effects such as maternal acidosis.