Tangier Disease Clinical Trial
Official title:
High Protein Diet , CRP and CVD Risk Factors
The investigators aimed to determine the effects of HP diet on CVD risk factors and hs-CRP among overweight and obese women.
Background: Studies regarding the effects of high protein (HP) diet on cardiovascular (CVD)
risk factors have reported contradictory results.
Objective: In present study, we aimed to determine the effects of HP diet on CVD risk
factors and hs-CRP among overweight and obese women.
Design: In this randomized controlled trial, we recruited 60 overweight and obese women,
aged 20-65 years into HP or control energy restricted diets for three months (protein,
carbohydrate, fat: 25%, 45%, 30% vs. 15%, 55%, 30%, respectively). Total protein amount,
divided to animal and plant sources in 50%-50% and animal sources distributed (half/half)
between meats and dairy products. Fasting blood samples, hs-CRP, lipid profile, systolic and
diastolic blood pressure and anthropometric measurements were measured based on the standard
guidelines.
;
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Health Services Research
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