Laser Therapy for Patients With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus Clinical Trial

Official title:

The Effect of Dental Laser Therapy for Patients With Systemic Lupus Erythematosus

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04453215
• Other study ID #: 1298
• Status: Completed
• Phase: N/A
• Start date: January 12, 2019
• Est. completion date: March 15, 2020

Study information

• Verified date: November 2021
• Source: Istanbul University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease that has detrimental effects on connective tissue and other organs. The musculoskeletal system is one of the most affected systems in this group of patients including the temporomandibular joint. The most common symptoms when muscle involvement in SLE are muscle atrophy decreased muscle strength and myopathy. SLE activity and long-term corticosteroid use are thought to be responsible for these symptoms, thus, SLE patients are accepted to be at higher risk for temporomandibular joint disorders (TMD). Low-level laser therapy(LLLT) is frequently used in the treatment of TMD due to its pain relief and anti-inflammatory effect. Thus, in this study, LLLT has been used to evaluate this treatment modality on the chewing function and pain values of SLE patients with myogenic TMD.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 91
• Est. completion date: March 15, 2020
• Est. primary completion date: December 23, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Having myogenic temporomandibular joint disorder,

• Following a stable medical regime,

• Showing minimum pain intensity of 50 mm on the visual analog scale.

Exclusion Criteria:

• Having concurrent systemic diseases,

• Using antimalarial drugs,

• Wearing removable prosthesis,

• History of facial trauma.

Related Conditions & MeSH terms

• Lupus Erythematosus, Systemic
• Muscle Pain
• Myalgia
• Systemic Lupus Erythematosus

Intervention

Device:
• GaAlAs semiconductor diode laser device
low-level laser therapy

Locations

Country	Name	City	State
Turkey	Istanbul university,Faculty of Dentistry	Fatih

Sponsors (1)

Lead Sponsor	Collaborator
Dr. Merve Benli

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	pain value	Pain intensity was evaluated by using Visual Analog Scale(VAS).	2 months
Primary	chewing function	The chewing function was evaluated by measuring the geometric mean diameter of crushed test food.	2 months