Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia

Syringomyelia Clinical Trial

Official title: Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia

Status Completed

Clinical Trial Summary

The purpose of this study is to determine whether a posterior fossa decompression or a posterior fossa decompression with duraplasty results in better patient outcomes with fewer complications and improved quality of life in those who have Chiari malformation type I and syringomyelia.

Clinical Trial Description

Participants with Chiari Malformation type I and syringomyelia will be randomized to either have a posterior fossa decompression done with or without duraplasty. The participant will then return to the neurosurgeon's office at the following time points which are consistent with standard of care practice: < 6 weeks, 3-6 months, and 12 months. At these visits, the clinician will complete a physical exam and the participant will report on the prognosis of symptoms and complete two quality of life questionnaires. A brain and cervical spine MRI will be performed 12 months after the decompression. ;

Related Conditions & MeSH terms

• Arnold-Chiari Malformation
• Arnold-Chiari Malformation, Type 1
• Chiari Malformation Type I
• Congenital Abnormalities
• Syringomyelia
• Type I Arnold-Chiari Malformation

• NCT number: NCT02669836
• Study type: Interventional
• Source: Washington University School of Medicine
• Status: Completed
• Phase: N/A
• Start date: April 2016
• Completion date: July 31, 2020