Clinical Trials Logo
  1. Home
  2. Syncope, Vasovagal
  3. NCT05572034

Cardiac Autonomic Denervation for Cardio-inhibitory Syncope — CardioSync  

Syncope, Vasovagal Clinical Trial

Official title:
Cardiac Autonomic Denervation for Cardio-inhibitory Syncope

Clinical Trial Summary

Background: Autonomic system modification is an established therapeutic approach that has been increasingly used for the treatment of vagal-related symptomatic bradycardia, such as cardio-inhibitory vasovagal syncope1-12. Although convincing results had been reported from small populations, a large randomized study providing robust evidence on the efficacy of this approach has not yet been performed. Hypothesis: Cardiac autonomic system modification is effective for the treatment of vagal-related symptomatic bradycardia, and is associated better clinical results as compared to placebo.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05572034
Study type Interventional
Source University of Sao Paulo General Hospital
Contact Mauricio I scanavacca, MD, PhD
Phone + 55 11 26615341
Email mauricio.scanavacca@incor.usp.br
Status Not yet recruiting
Phase N/A
Start date September 1, 2023
Completion date March 30, 2024
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05555771 - Paediatric Syncope in the Emergency Department N/A
Completed NCT06038708 - Head-up Tilt Test in Patients With Reflex Syncope and Asystolic Response Who Received a Dual-chamber Pacemaker With the Closed Loop Stimulation (CLS) and Participated in the BIOSync Trial
Recruiting NCT03159156 - Respiration and Applied Tension Strategies to Reduce Vasovagal Reactions to Blood Donation N/A
Completed NCT05729724 - Effect of Pharmacological Interventions on Systolic Blood Pressure Drops (SynABPM 2 Proof-of-concept)
Recruiting NCT04595942 - Midodrine and Fludrocortisone for Vasovagal Syncope Phase 3
Completed NCT03903744 - Cardioneuroablation for Reflex Syncope N/A
Completed NCT05782647 - Wearable Monitor in Patients With Syncope N/A
Completed NCT00465439 - Safety/Efficacy Study of Local Anesthetic Prior to Femoral Artery Sheath Removal N/A
Active, not recruiting NCT01621464 - Closed Loop Stimulation for Neuromediated Syncope (SPAIN Study) Phase 4
Recruiting NCT06458140 - Cardioneuroablation and Ventricular Proarrhythmia N/A
Recruiting NCT06440291 - Cardioneuroablation for Reflex Syncope and Exercise Capacity N/A
Recruiting NCT06336031 - Impact of Blood Phobia on Fainting Susceptibility N/A
Completed NCT01617616 - Tilt Table With Suspected Postural Orthostatic Tachycardia Syndrome (POTS) Subjects N/A
Recruiting NCT05086679 - Compression Stockings for Treating Vasovagal Syncope Trial N/A
Completed NCT04772755 - Presyncope (Syncope) Prevention Study N/A
Completed NCT03533829 - Preventing Post-Vaccination Presyncope and Syncope in Adolescents Using Simple, Clinic-based Interventions: A Pilot Study N/A
Completed NCT05782699 - Detecting Syncope by an Integrated Multisensor Patch-type Recorder N/A
Completed NCT01695525 - Influence of Yoga in Patients With Neurocardiogenic Syncope Phase 0
Completed NCT00475462 - The Effectiveness of Metoprolol in the Prevention of Syncope Recurrence in Children and Adolescents N/A
Completed NCT04972123 - The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope Phase 2