Suspected Acute Myocarditis Clinical Trial
Official title:
Value of CMR Including T1 Mapping in Patients With Acute Myocarditis
To evaluate the additive values of T1 mapping in patients with acute myocarditis.
Cardiac magnetic resonance (CMR) is an established non-invasive diagnostic tool for acute
and chronic myocarditis. Established CMR criteria for diagnosing myocarditis are edema on
black-blood T2-weighted imaging, relative contrast enhancement seen on T1-weighted imaging
for assessment of hyperemia, and late contrast-agent enhancement seen with inversion
recovery late enhancement technique for visualization of myocardial fibrosis.
Recently, tissue characterization based on calculation of myocardial T1 relaxation time (T1
mapping) as well as T1-derived extracellular volume fraction has become available. Recently,
reference values for myocardial T1 relaxation times at 3T for healthy volunteers were
published for CMR. However, to date no comprehensive data for multiparametric CMR in
patients with suspected myocarditis at 3 Tesla is available. Therefore, the purpose of this
prospective study was to evaluate the diagnostic value of CMR at 3T in patients with
suspected acute myocarditis using a multiparametric CMR approach including T1 mapping as
novel tool for tissue characterization.
CMR will be performed within 7 days after hospital admission for "suspected acute
myocarditis".
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Observational Model: Cohort, Time Perspective: Prospective