Recolonization Following Preoperative Disinfection Plastic Adhesive Drapes

Status Completed

Clinical Trial Summary

The purpose of this study is to measure the time to recolonization intraoperatively after preoperative disinfection with chlorhexidine solution in ethanol and to determine evidence of differential bacterial growth with or without plastic adhesive drape on the chest as well as with or without microbial sealant on the leg.

Clinical Trial Description

The purpose of this study is to measure the time to recolonization intraoperative after preoperative disinfection with chlorhexidine solution in ethanol and to determine evidence of differential bacterial growth with or without plastic adhesive drape as well as with or without microbial sealant on the leg. A RCT study of 140 patients undergoing coronary artery bypass grafting (CABG) and/or aortic valve replacement (AVR) are included. The investigators test the hypothesis that patients randomized to no plastic adhesive drape intraoperatively will have a reduced recolonisation compared to patients with plastic adhesive drape. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01316588
Study type	Interventional
Source	Örebro University, Sweden
Contact
Status	Completed
Phase	Phase 3
Start date	August 2010
Completion date	October 2011

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05529173` - Povidone-Iodine for Nasal Decolonization	Phase 4
Recruiting	`NCT03295955` - Comparing Efficacy of Postoperative Oral Antibiotic Use in Trans-Oral Thyroidectomy	N/A
Not yet recruiting	`NCT05276687` - Efficacy of Diluted Betadine vs Antibiotic Installation Before Surgical Wound Closure in Prevention of Post Cardiac Surgery Wound Infection	Phase 4
Completed	`NCT02776774` - Topical Antibiotic Treatment for Spine Surgical Site Infection
Terminated	`NCT00386477` - Vaginal Cleansing at Cesarean Delivery to Reduce Infection: A Randomized, Controlled Trial	N/A
Not yet recruiting	`NCT03872544` - Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
Recruiting	`NCT05077592` - Addition of Pre-wound Closure Povidone Iodine Wash Versus Direct Wound Closure Effect on Surgical Site Infections	Phase 4
Completed	`NCT03148067` - Incidence and Risk Factors for Surgical Site Infection After Intramedullary Nailing of Femoral and Tibial Fractures
Enrolling by invitation	`NCT03880188` - Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
Completed	`NCT01890720` - Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following Caesarean Section	N/A
Recruiting	`NCT06319235` - Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG®	Phase 1/Phase 2
Completed	`NCT02919410` - Bacterial Colonization With and Without Iodophor-impregnated Adhesive Drapes in Hip Surgery: a Prospective, Randomized Trial	N/A
Completed	`NCT02020018` - Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection	N/A
Completed	`NCT01741649` - Clorhexidine Versus Povidone for the Prevention of Surgical Site Infection After Cesarean Section	N/A
Completed	`NCT01340534` - Supplemental Perioperative Oxygen to Reduce the Incidence of Post-cesarean Wound Infection	Phase 3
Not yet recruiting	`NCT01457859` - Effectiveness of Triclosan Coated Sutures in Preventing Leg Wound Infection After Coronary Artery Bypass Surgery	Phase 4
Completed	`NCT03365219` - Alexis O-Ring Wound Retractor for the Prevention of Post-cesarean Surgical Site Infections	N/A
Completed	`NCT01026259` - Local Warming of Surgical Incisions	Phase 3
Completed	`NCT03574090` - Study the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Infection in Colorectal Surgery	Phase 4
Completed	`NCT03199911` - Topical Antibiotic Prophylaxis for Eyelids	Phase 4