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PVP Iodine vs Chlorhexidine in Alcohol for Disinfection of the Surgical Site — PICASSo  

Surgical Site Infections Clinical Trial

Official title:
Polyvinylpyrrolidone (PVP) Iodine vs Chlorhexidine in Alcohol for Disinfection of the Surgical Site: a Cluster-randomized Multicenter Trial

Clinical Trial Summary

Prospective cluster-randomized multicenter cross-over trial to prove non-inferiority of PI compared to CHX in preoperative skin antisepsis

Clinical Trial Description

Surgical site infections (SSIs) are the most common nosocomial infections in surgical patients causing significant increases in morbidity, mortality, and health care costs. As they are usually caused by components of the normal skin flora, disinfection of the surgical site with an antiseptic skin preparation is standard practice prior to any surgical intervention. The most commonly used disinfectants are either chlorhexidine in alcoholic solution (CHX) or PVP iodine in alcoholic solution (PI) This prospective cluster-randomized multicenter cross-over trial is to prove non-inferiority of PI compared to CHX in preoperative skin antisepsis in abdominal and cardiothoracic surgery in regard of SSIs. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03685604
Study type Interventional
Source University Hospital, Basel, Switzerland
Contact
Status Completed
Phase Phase 4
Start date September 10, 2018
Completion date June 30, 2020
View Details
See also
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