Antibiotics After Breast Reduction:Clinical Trial With Randomization

Status Completed

Clinical Trial Summary

This study was designed to determine the role of antibiotics reduction mammaplasty influence surgical site infections rates.

Clinical Trial Description

Prevention of SSI is important due to its morbidity, longer hospital stays and higher costs. In many surgical procedures where the risk of infection is relatively low and the postoperative infection can be treated properly, the role of antibiotics is not clear.

Despite the lack of evidence from prospective randomized controlled trials of evaluation, the use of antibiotics in plastic surgery is widespread in order to offer the highest safety standards patients.

The breast reduction is defined as "clean surgery" with a lower infection rate to 3.4%. Thus, the antibiotic is not recommended. However, studies have shown a real rate of infection associated with procedures ranging from 4-36%.

Thus, this trial was designed to verify the role of antibiotics in reduction mammaplasty. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02569866
Study type	Interventional
Source	Federal University of São Paulo
Contact
Status	Completed
Phase	Phase 2
Start date	November 2014
Completion date	August 2016

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT04096885` - The Inselspital Surgical Cohort Study
Terminated	`NCT03820648` - Wound Protector Dual-ring Alexis® in Pancreaticoduodenectomy	N/A
Completed	`NCT04067843` - Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study	N/A
Terminated	`NCT04042077` - Delafloxacin IV and OS Administration Compared to Best Available Therapy in Patients With Surgical Site Infections	Phase 3
Completed	`NCT05841576` - Anaesthetic Management Guided by COMET Measurements	N/A
Withdrawn	`NCT05338281` - NPWT for Abdominal Incisions in DIEP Reconstructions: A RCT	N/A
Recruiting	`NCT03042091` - Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery	Early Phase 1
Completed	`NCT01697748` - Prospective Study on Cesarean Wound Outcomes	N/A
Terminated	`NCT01789697` - Text Message Study	N/A
Recruiting	`NCT05966961` - Novosyn® CHD vs Polyglactin 910 Suture to Close Wounds After Emergency or Elective Laparotomy or Laparoscopic Surgery
Recruiting	`NCT05077592` - Addition of Pre-wound Closure Povidone Iodine Wash Versus Direct Wound Closure Effect on Surgical Site Infections	Phase 4
Recruiting	`NCT05763602` - PVI to Prevent S. Aureus SSI After Fixation of HELEF (POTENT Study)	Phase 4
Recruiting	`NCT05502380` - Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery	Phase 3
Recruiting	`NCT03221023` - Intrawound Vancomycin Prophylaxis for Neural Stimulator	Phase 2/Phase 3
Completed	`NCT03257202` - Topical Treatment and Prevalence of P. Acnes	Phase 2
Completed	`NCT06154720` - Surgical Site Infection After Episiotomy Repair Related to Routine Use of Antibiotic Prophylaxis in Low-Risk Population
Not yet recruiting	`NCT06465901` - A Stratified, Multi-ARm, muLti-site Randomised Platform Trial Aiming to Reduce the INcidence of Post-operative SSI	N/A
Not yet recruiting	`NCT04820075` - Efficacy of an Intervention to Improve the Preoperative Shower in Scheduled Surgery	N/A
Recruiting	`NCT03561376` - Zinc Oxide Versus Petrolatum Following Skin Surgery	Early Phase 1
Not yet recruiting	`NCT04496180` - Prevena to Prevent Surgical Site Infection After Emergency Abdominal Laparotomy	N/A