New Techniques to Reduce Intra-operative Bleeding During Complex Liver Resection

Surgical Blood Loss Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02996006
• Other study ID #: TJ-liver-200804
• Status: Completed
• Phase: N/A
• First received: December 12, 2016
• Last updated: December 16, 2016
• Start date: November 2009

Study information

• Verified date: December 2016
• Source: Tongji Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: China: Ministry of Health
• Study type: Observational [Patient Registry]

Clinical Trial Summary

This observational study introduced an new advanced bleeding control strategy during complex liver resection.This newly described "stepwise vascular control" technique was efficacious and feasible to control intra-operative bleeding in complex hepatectomy involving second hepatic hilum and retro-hepatic inferior vena cava.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. primary completion date: July 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 41 Years to 68 Years

Eligibility

Inclusion Criteria:

• tumor size is more than 5cm in diameter;

• these tumor were close to or were compressing main hepatic veins and RIVC directly;

• Pugh-Child Grade is A or Indocyanine green retention rate at 15min (ICG15%) is less than 10% .

Study Design

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Blood Loss, Surgical
• Surgical Blood Loss

Intervention

Procedure:
• stepwise vascular control
Before liver parenchymal resection, we performed "total hepatic vascular preparation for occlusion" with portal triad (PT), infra-hepatic inferior vena cava (IIVC), and supra-hepatic inferior vena cava (SIVC) preparation in order. Then we performed step-by-step vascular occlusion according to the individual bleeding situation.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Tongji Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	blood loss during liver resection		duration of operation time	Yes