Safety & Efficacy of Paramedic Treatment of Regular Supraventricular

Status Recruiting

Clinical Trial Summary

Supraventricular tachycardia (SVT) is a term describing any rhythm coming from the top half of the heart. Although atrial fibrillation is the commonest cardiac arrhythmia, regular SVT's are also common. The two commonest regular SVT's are atrioventricular (nodal) reentry tachycardias (AV(N)RT) and atrial flutter (AFL). Atrioventricular (nodal) reentry tachycardias (AV(N)RT) are common but benign forms of fast heart rhythm. Although AV(N)RT can cause unpleasant symptoms and are frightening it is not dangerous. If patients present with AV(N)RT the accepted and normal treatment for most is to have the fast heart rhythm stopped by either taking a deep breath and straining or by the use of drugs. Patients can then be discharged home and have further investigation and treatment as an outpatient. SVT can be frightening for the patient but is easy to diagnose and treat. There is high success rate post treatment for this benign condition. This is traditionally done in the local accident and emergency, although patients can sometimes be unnecessarily admitted to hospital overnight. We propose to investigate the safety and efficacy of training paramedics to treat safe forms of AV(N)RT at the scene and then giving the patient an information pack which includes a request for a GP referral to a heart rhythm specialist. Patients will be randomly allocated after consenting to take part in the study to either get paramedic or accident and emergency department treatment. We will compare these two approaches by telephone follow up of the patients. The costs of the different approaches will be compared by assessing the rate of appropriate investigation and the information given to patients and how they rated their experiences.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02216240
Study type	Interventional
Source	Barts & The London NHS Trust
Contact	Victoria Baker, RN MSc
Phone	02034656763
Email	victoria.baker@bartshealth.nhs.uk
Status	Recruiting
Phase	N/A
Start date	December 2010

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT03153072` - Evaluation of the Pharmacokinetic Profile, Pharmacodynamic Effects, Acceptability and Tolerability of an Oral Amiodarone Solution of 15 mg / mL in Children With Supra Ventricular Tachycardia	Phase 2
Completed	`NCT02469623` - Dipole Density Mapping in Supraventricular Tachycardia	N/A
Completed	`NCT02469649` - Dipole Density Mapping of Supraventricular Tachycardia	N/A
Completed	`NCT01921660` - Dipole Density Mapping in Right (and Left) SVT	N/A
Completed	`NCT02469636` - Dipole Density Mapping in Supraventricular Tachycardia	N/A
Completed	`NCT02952781` - Comparison of Continuous Sternal ECG Patch Monitors (Carnation and Zio) Trial	N/A
Completed	`NCT00390546` - Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia	Phase 3
Completed	`NCT05531903` - High-density Activation Mapping of the Slow Pathwayto Guide Catheter Ablation in Patients With Typical Atrioventricular Nodal Reentrant Tachycardia	N/A
Recruiting	`NCT05022290` - Double-syringe vs Single-syringe Technique of Adenosine for Termination of Regular Narrow Complex Tachycardia	N/A
Terminated	`NCT01216501` - Sevoflurane and Isoflurane for RF or Cryo Ablation in Children.	N/A
Completed	`NCT00787800` - The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock	Phase 4
Completed	`NCT04051541` - Simulation of Adenosine Push Methods for Treatment of SVT Using Agitated Saline Visualized by Ultrasound	N/A
Not yet recruiting	`NCT06344494` - Cardiac Interventional ICE Imaging Trial	N/A
Completed	`NCT01426425` - Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia	Phase 3
Not yet recruiting	`NCT03528616` - Management of Supraventricular Tachycardia of Children
Completed	`NCT01875614` - Dipole Density Mapping in Supraventricular Tachycardia	N/A
Recruiting	`NCT01584154` - Comparative Study Between Cryoablation and Radiofrequency Ablation in the Treatment of Supraventricular Tachycardia	Phase 4
Recruiting	`NCT05521451` - Clinical Cohort Study - TRUST
Enrolling by invitation	`NCT02031484` - Comparison of Continuous Sternal ECG Patch Monitors (Carnation and Zio) Trial	N/A
Not yet recruiting	`NCT02126631` - Sternal ECG Patch Comparison Trial	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Safety and Efficacy of Paramedic Treatment of Regular Supraventricular Tachycardia — Para-SVT

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms