Sodium Bicarbonate Supplementation in Athletes

Supplementation Clinical Trial

Official title:

The Effect of Sodium Bicarbonate Supplementation on Physical Capacity and Body Composition in Trained Athletes

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03165357
• Other study ID #: ULS00002
• Status: Completed
• Phase: Phase 3
• First received: May 22, 2017
• Last updated: May 23, 2017
• Start date: October 10, 2015
• Est. completion date: April 5, 2016

Study information

• Verified date: May 2017
• Source: Poznan University of Life Sciences
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on body composition, physical capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Description:

Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive- dose NaHCO3 ingestion on physical capacity, body composition and concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 26
• Est. completion date: April 5, 2016
• Est. primary completion date: March 10, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 43 Years

Eligibility

Inclusion Criteria:

• written consent to participate,

• a current medical clearance to practice sports,

• training experience: at least 2 years (of CrossFit training),

• minimum of 3 workout sessions (CrossFit) a week,

• 20-43 years.

Exclusion Criteria:

• current injury,

• any health-related contraindication,

• declared general feeling of being unwell,

• unwilling to follow the study protocol.

Related Conditions & MeSH terms

• Sport
• Supplementation

Intervention

Dietary Supplement:
• Sodium bicarbonate supplementation

• Placebo treatment

Locations

Country	Name	City	State
Poland	Poznan University of Life Sciences, ul.Wojska Polskiego 31	Poznan	Wielkopolska

Sponsors (2)

Lead Sponsor	Collaborator
Poznan University of Life Sciences	Department of Biochemistry, Poznan University of Physical Education, Poland

Country where clinical trial is conducted

Poland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes in aerobic capacity after sodium bicarbonate supplementation	The incremental cycling test (ICT)	Baseline and after 10 days
Primary	Changes in specific performance capacity after sodium bicarbonate supplementation	The CrossFit-specific physical fitness test: Fight Gone Bad (FGB)	Baseline and after 10 days
Secondary	Changes in fat mass and fat free mass after sodium bicarbonate supplementation	Fat mass (kg) and fat free mass (kg) analysis	Baseline and after 10 days
Secondary	Changes of red and white blood cell concentration in blood after sodium bicarbonate supplementation	Red blood cells (RBC) [mln/mm³] and white blood cells (WBC) [mln/mm³] concentration analysis	Baseline and after 10 days
Secondary	Changes in blood glucose and hemoglobin concentration after sodium bicarbonate supplementation	Hemoglobin (Hb) [g/dl] and glucose [g/dl] concentration analysis	Baseline and after 10 days
Secondary	Changes in blood hematocrit levels after sodium bicarbonate supplementation	Hematocrit (HCT) [%] level analysis	Baseline and after 10 days
Secondary	Changes of lactate and pyruvate concentration in blood after sodium bicarbonate supplementation	Lactate [mmol/L] and pyruvate [mmol/L] concentration analysis	Baseline and after 10 days
Secondary	Changes of creatine kinase and lactate dehydrogenase activity in blood after sodium bicarbonate supplementation	Creatine kinase [U/L] and lactate dehydrogenase [U/L] activity analysis	Baseline and after 10 days