Effects of Psychiatric Admissions on Self-harm and Suicide in People With Borderline Personality Disorder

Suicide Clinical Trial

Official title:

Effects of Psychiatric Admissions on Self-harm and Suicide in People With Borderline Personality Disorder

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06424509
• Other study ID #: 2024-00589-01
• Status: Not yet recruiting
• Start date: September 1, 2024
• Est. completion date: January 1, 2027

Study information

• Verified date: June 2024
• Source: Lund University
• Contact: Sofie Westling, MD, PhD
• Phone: +46735626099
• Email: sofie.westling[@]med.lu.se
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The current study aims to evaluate the impact of long (>5 days) and/or compulsory psychiatric inpatient care on subsequent healthcare utilization for self-harm and suicide in people with borderline personality disorder, a condition characterized by frequent self-harm. The basis for this study is the diversity of clinical practices across Swedish regions. By categorizing clinics based on their practices with respect to long and/or compulsory psychiatric inpatient care, it is possible to explore the impact of these practices on subsequent somatic and psychiatric healthcare, including emergency care due to self-harm as well as on completed suicides. All psychiatric clinics across Sweden authorized to administer compulsory care for adults, totalling 78 clinics will be included. Each clinic per specific calendar year will represent one participant, identified by the clinic's name and the respective year (e.g., Umeå2010, Linköping2013, Malmö2022). Data collection will involve the utilization of the national registers to capture outcome measures and account for confounding factors. The participants will be ranked based on a composite variable, which includes the average number of days spent in inpatient compulsory care and other psychiatric inpatient care exceeding 5 days, among individuals diagnosed with BPD. The top quartile of participants will be compared with the bottom quartile.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 390
• Est. completion date: January 1, 2027
• Est. primary completion date: January 1, 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Psychiatric clinic in Sweden authorized to administer compulsory care for adults. Each clinic per specific calendar year will represent one participant, identified by the clinic's name and the respective year (e.g., Umeå2010, Linköping2013, Malmö2022).

Exclusion Criteria:

• No authorization to administer compulsory care for adults

Related Conditions & MeSH terms

• Borderline Personality Disorder
• Non-suicidal Self-injury
• Personality Disorders
• Self-harm
• Self-Injurious Behavior
• Suicide

Intervention

Other:
• High degree of long (>5 days) and/or compulsory psychiatric inpatient care
High degree of long (>5 days) and/or compulsory psychiatric inpatient care

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Lund University	Linkoeping University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of healthcare visits due to self-harm	Number of healthcare visits due to self-harm in specialized inpatient or outpatient care, as defined in the NPR (X60-X84; Intentional self-harm) divided by the number of individuals diagnosed with BPD per clinic and calendar year.	1 year
Primary	Number of deaths by suicide	Number of deaths by suicide (X60-X84; Intentional self-harm or Y10-34; Events of undetermined intent) in individuals diagnosed with BPD divided by the number of individuals diagnosed with BPD per clinic and calendar year.	1 year
Primary	Number of deaths by suicide within 30 days after discharge	Number of deaths by suicide (X60-X84; Intentional self-harm or Y10-34; Events of undetermined intent) within 30 days after discharge, in individuals diagnosed with BPD divided by the number of individuals diagnosed with BPD, per clinic and calendar year	1 year
Secondary	Number of days between admissions to psychiatric inpatient care	Number of days between admissions to psychiatric inpatient care for people diagnosed with BPD divided by the number of individuals diagnosed with BPD per clinic and calendar year.	1 year
Secondary	Number of days between death by suicide and discharge	Number of days between death by suicide (X60-X84; Intentional self-harm or Y10-34; Events of undetermined intent) and discharge in individuals diagnosed with BPD. For this variable, death by suicide during inpatient admission will be labelled 0.	1 year
Secondary	Number of days in somatic (non-psychiatric) inpatient care after self-harm	Number of days in somatic (non-psychiatric) inpatient care after self-harm (X60-X84; Intentional self-harm) divided by the number of individuals diagnosed with BPD per clinic and calendar year.	1 year