Emotional Prosody Recognition and Decision Making Inf fMRI and Vulnerability to Suicide — EMODES  

Suicide Clinical Trial

Official title: Emotional Prosody Recognition and Decision Making Inf fMRI and Vulnerability to Suicide

Status Recruiting

Clinical Trial Summary

Suicide is known to be frequent in depression, and in most of the psychiatric diseases. But as it can occur in patients with no psychiatric illness and doesn't occur in every patients with psychiatric illness, it has to be considered henceforth as a specific vulnerability.

This trial will study two fMRI paradigms, emotional prosody recognition and decision making, in order to characterize emotional and cognitive trait factors in a population of patients vulnerable to suicide. Four different groups will be constituted : depressed suicide attempters, depressed patients with past history of suicidal acts, depressed patients with no history of suicidal acts and healthy controls.

The main goal will be to correlate fMRI activation during the two paradigms in subjects vulnerable to suicide. The secondary goals will be to characterize emotional and cognitive trait factors in these subjects, to demonstrate that those characteristics are independent from depression and to correlate these trait factors with socio-demographic and clinical features with fMRI activations.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Suicide

• NCT number: NCT02901769
• Study type: Interventional
• Source: Rennes University Hospital
• Contact: David Travers, MD
• Phone: 02 99 28 67 67
• Email: david.travers@chu-rennes1.fr
• Status: Recruiting
• Phase: N/A
• Start date: February 2013
• Completion date: February 2020