Ketamine + Cognitive Training for Suicidality in the Medical Setting

Status Enrolling by invitation

Clinical Trial Summary

This project seeks to identify the acute and longer-term impact of a single dose of intravenous ketamine among suicidal patients referred for psychiatric consultation/liaison in the medical inpatient setting. The investigators will then test whether ketamine's rapid effects can be extended by introducing helpful information delivered by a computer-based training protocol. This work could ultimately lead to the ability to treat suicidality more efficiently and with broader dissemination by rapidly priming the brain for helpful forms of learning.

Clinical Trial Description

NOTE: Edits were made to the outcome measures sections to improve clarity regarding the a priori analytic plan with respect to the "Time Frame" of measurements and to reduce redundancies. Timepoints that will be analyzed as trajectories over windows of time and measurements that will be analyzed as composites are now more clearly specified. The previous entries correctly identified all relevant measures and timepoints, but implied incorrectly that each timepoint/measure would be analyzed in isolation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04578938
Study type	Interventional
Source	University of Pittsburgh
Contact
Status	Enrolling by invitation
Phase	Phase 4
Start date	March 15, 2021
Completion date	March 2, 2026

View Details

See also
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