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Subcutaneous Fat clinical trials

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NCT ID: NCT05234736 Completed - Subcutaneous Fat Clinical Trials

A Study to Evaluate the Pharmacokinetic Profile of CBL-514 Injection in Healthy Volunteers

Start date: February 11, 2022
Phase: Phase 2
Study type: Interventional

This Phase 2 study will be an open-label and single course study to assess the safety, tolerability, PK and metabolite profile of CBL-514.

NCT ID: NCT04897412 Completed - Subcutaneous Fat Clinical Trials

A Study to Evaluate the Efficacy, Safety, and Tolerability of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 2)

Start date: February 14, 2022
Phase: Phase 2
Study type: Interventional

The Stage 2 of this phase 2 study will be a randomized, single-blind, placebo-controlled, parallel, and multiple-dose study to assess the efficacy, safety, and subject satisfaction of CBL-514.

NCT ID: NCT04699669 Completed - Subcutaneous Fat Clinical Trials

A Phase 1 Study to Evaluate the Safety and Tolerability of CBL-514 Injection on Convexity or Fullness of Abdominal Subcutaneous Fat in Healthy Volunteers

Start date: November 27, 2018
Phase: Phase 1
Study type: Interventional

The Phase 1 component of the study is a double-blind, placebo-controlled, single ascending dose (SAD) design intended to assess the safety, tolerability, and PK of CBL-514. The SAD part will involve 9 proposed dosing cohorts.

NCT ID: NCT04698642 Completed - Subcutaneous Fat Clinical Trials

A Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of CBL-514 Injection for Reducing Convexity or Fullness of Abdominal Subcutaneous Fat

Start date: February 3, 2020
Phase: Phase 2
Study type: Interventional

The Phase 2a component of the study will be a randomized, open-label, parallel, and multiple dose study to further examine the safety and efficacy profile of 3 CBL-514 dose levels based on the results from Phase 1 of the study.

NCT ID: NCT04575467 Completed - Subcutaneous Fat Clinical Trials

A Study to Evaluate the Efficacy, Safety and Tolerability of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 1)

Start date: December 9, 2020
Phase: Phase 2
Study type: Interventional

The Stage 1 of this phase 2 study is an open-label single ascending dose (SAD) study. The primary objectives are to evaluate the safety and tolerability of injection lipolysis with CBL-514. It will be followed by a parallel-arm multiple-dose design in Stage 2.

NCT ID: NCT03871556 Completed - Subcutaneous Fat Clinical Trials

Diagnostic Ultrasound for Measuring Fat of the Body

Start date: March 20, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to provide information about human subcutaneous fat thickness at different anatomic sites on the body by measuring these thicknesses with a diagnostic ultrasound and also by correlating patient perceptions of body image with measured fat distribution. Subjects currently living in the Chicago metropolitan area and meet inclusion/exclusion criteria will be considered for enrollment.

NCT ID: NCT03682471 Completed - Subcutaneous Fat Clinical Trials

Long-term 24-month Follow-up Study on Safety and Maintenance of Efficacy of ATX-101 (Sodium Deoxycholate Injection)

Start date: February 14, 2012
Phase:
Study type: Observational

The objective of this non-treatment, placebo-controlled, observational, 24-month follow-up study was to evaluate the long-term efficacy and safety of subcutaneous (SC) injections of deoxycholic acid (ATX-101) in the submental area. No treatment was administered in this study. Participants who previously received deoxycholic acid injections in studies ATX-101-10-16 [NCT01305577] or ATX-101-10-17 [NCT01294644] were enrolled in this non-treatment observational follow-up study to further evaluate safety and efficacy.

NCT ID: NCT02539043 Completed - Subcutaneous Fat Clinical Trials

Effects of Ultrasound Cavitation Focused on Located Adiposity

Start date: January 2015
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of cavitation ultrasound focused on localized adiposity and its effects associated with stereodynamic lymphatic drainage. The investigators aim also to know if this procedure will influence the biochemical profile of the individuals concerned, as well as whether it will be found difference between the group that will receive focused ultrasound cavitation associated with stereodynamic drainage and the group will receive only focused cavitation ultrasound.

NCT ID: NCT02512822 Completed - Subcutaneous Fat Clinical Trials

Usefulness of Non-invasive Radiofrequency Therapy for Facial Contouring

UNIRFFC
Start date: November 2013
Phase: N/A
Study type: Interventional

To evaluate the efficacy of novel noninvasive RF technology for reduction of submental fat.

NCT ID: NCT02098811 Completed - Subcutaneous Fat Clinical Trials

Evaluation of the Safety and Precursors of Efficacy

Start date: June 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate and compare the safety and pre-cursors of efficacy of a non-invasive 1064nm laser and 940nm diode, for the disruption of subcutaneous adipose tissue and skin tightening.