Transcranial Alternating Current Stimulation Prevents Delirium in Patients

Status Recruiting

Clinical Trial Summary

The goal of this clinical trial is to learn about using the latest transcranial alternating current stimulation (tACS) to reduce the incidence of delirium in patients with subarachnoid hemorrhage. The main question it aims to answer is: • To evaluate the effect of tACS on reducing delirium in patients with subarachnoid hemorrhage. Participants will treated with real tACS or sham tACS. Researchers will mainly compare the two groups to see if patients' delirium will reduce by using tACS.

Clinical Trial Description

Research objectives: To reduce the incidence of delirium in patients with subarachnoid hemorrhage by using the latest transcranial alternating current stimulation. Research contents: 1. To evaluate the effect of transcranial alternating current stimulation on improving sleep quality in patients with subarachnoid hemorrhage; 2. To evaluate the effect of transcranial alternating current stimulation on reducing delirium in patients with subarachnoid hemorrhage. Research hypothesis: Transcranial alternating current stimulation can improve sleep quality and reduce the incidence of delirium in patients with subarachnoid hemorrhage. Study design: 1. double-blind randomized clinical trial 2. Subjects：Patients with subarachnoid hemorrhage admitted to the neurosurgical intensive care unit during the study period. 3. Number of participating centers and names of centers: Single research center, Xuanwu Hospital, Beijing 4. Sample size: The total number of plans was 74, and the total number of study centers was 74. 5. Grouping of subjects：The random number table method was used for randomization, and the envelope method was used for randomization. The random serial number was stored in an airtight envelope, a patient was admitted, and an envelope was opened. 6. Intervention measures: ① The control group was treated with sham transcranial electrical stimulation; ② The experimental group was treated with real transcranial electrical stimulation. 7. Outcome measures: ① Efficacy indicators: the incidence and duration of delirium; The scores of Richard Campell sleep questionnaire, Hamilton Anxiety Scale, Mini-Mental State Examination, numerical rating scale for pain and muscle strength were recorded.② Safety indicators: the incidence of adverse reactions. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06375408
Study type	Interventional
Source	Xuanwu Hospital, Beijing
Contact	Jun Wang, master
Phone	+86-010-83922775
Email	wangj229@126.com
Status	Recruiting
Phase	N/A
Start date	March 24, 2024
Completion date	March 24, 2026

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Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Transcranial Alternating Current Stimulation Prevents Delirium in Patients With Subarachnoid Hemorrhage — TACS

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms