Speech Processing in Stuttering

Stuttering Clinical Trial

Official title:

Speech Processing in Stuttering

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04929184
• Other study ID #: HUM00194953
• Secondary ID: 1R21DC019429-01
• Status: Recruiting
• Phase: N/A
• Start date: April 4, 2022
• Est. completion date: June 2025

Study information

• Verified date: June 2024
• Source: University of Michigan
• Contact: Emily Garnett, PhD
• Phone: 734-232-3371
• Email: emilyog[@]umich.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech. Eligible participants enrolled will complete a variety of computer and speech-based tasks on up to 2 visits.

Description:

The study team will update the record to include the secondary identification number once the NIH has released the funds.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 140
• Est. completion date: June 2025
• Est. primary completion date: June 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 6 Years to 65 Years

Eligibility

Inclusion Criteria (adults who do not stutter):

• 18-65 years old

• English as primary language

• Normal speech, language, hearing, cognition

Exclusion criteria: (adults who do not stutter)

• Personal or family history of stuttering

• Major medical or psychiatric illness

Inclusion criteria: (adults who stutter)

• Aged 18-65 years

• English as primary language

• Normal speech, language, hearing, cognition (other than stuttering)

• Currently stutters

Exclusion criteria: (adults who stutter)

• Speech therapy within the past year

• Major medical or psychiatric illness

Inclusion criteria: (children who do not stutter)

• Aged 6 to 17 years

• English as primary language

• Normal speech, language, hearing, cognition

Exclusion criteria: (children who do not stutter)

• Personal or family history of stuttering

• Major medical or psychiatric illness

• Language/motor delay

Inclusion criteria: (children who stutter)

• Aged 6 to 17 years

• English as primary language

• Normal speech, language, hearing, cognition (other than stuttering)

• Currently stutters

Exclusion criteria: (children who stutter)

• Major medical or psychiatric illness

• Language/motor delay

Related Conditions & MeSH terms

• Stuttering
• Stuttering, Adult
• Stuttering, Childhood

Intervention

Behavioral:
• Speech and non-speech tasks
Participants will complete speech tasks such as listening to and/or producing speech and non-speech sounds.

Locations

Country	Name	City	State
United States	University of Michigan	Ann Arbor	Michigan
United States	Michigan State University	East Lansing	Michigan

Sponsors (2)

Lead Sponsor	Collaborator
University of Michigan	National Institute on Deafness and Other Communication Disorders (NIDCD)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Phase locking value (PLV) - Session 1 speech tasks	The degree of synchronization will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals.	Session 1 (up to 4 hours)
Primary	Phase locking value (PLV) - Session 2 speech tasks	The degree of synchronization will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals. Session 2 is for adults only.	Session 2 (up to 4 hours)
Secondary	Phase locking value (PLV) - Non-speech tasks	The degree of synchronization will be measured by computing the PLV between subject's produced response and the auditorily presented stimuli. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals.	Session 1 (up to 4 hours)