Stuttering, Childhood Clinical Trial
Official title:
The Influence of Contextual and Constitutional Emotional Processes on Speech Motor Control and Speech Motor Learning in Early Childhood Stuttering
This study will compare speech variability between preschool-age children who stutter and typically fluent, age-matched peers. Differences in emotional reactivity, regulation and speech motor control have been implicated in stuttering development in children. This study seeks to understand further how these processes interact. Children will repeat a simple phrase after viewing age-appropriate images of either negative or neutral valence to assess speech motor control.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | March 1, 2024 |
Est. primary completion date | February 28, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 3 Years to 10 Years |
Eligibility | Inclusion Criteria: 1. English as the primary language of communication. 2. No history of neurological diseases or diagnosed speech-language disorders apart from stuttering. 3. Parent report or direct observation of oral-facial structural abnormalities (such as cleft lip and/or cleft palate). 4. Free of any medications that may affect neural functions (e.g., medications of seizures). 5. Normal hearing acuity (must pass a hearing screening). 6. Normal vision per parent report. Exclusion Criteria: 1. Failure to meet the inclusionary criteria listed above 2. Parental report of neurodevelopmental disorders (such as autism spectrum disorders) 3. Parental report of vision problems that are not corrected or corrected with glasses. |
Country | Name | City | State |
---|---|---|---|
United States | Syracuse University, Department of Communication Sciences and Disorders | Syracuse | New York |
Lead Sponsor | Collaborator |
---|---|
Syracuse University | National Institute on Deafness and Other Communication Disorders (NIDCD) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The spatiotemporal index (STI) of lip aperture during a negative valence condition on Day 1 (pretest). | The spatiotemporal index (STI), a measure of speech coordination developed by Smith and colleagues (e.g., Smith, Goffman, Zelaznik, Ying & McGillem, 1995). It will be employed to quantify speech motor control ability and speech motor learning effects. The STI reflects the degree to which repeated performance of a task produces movement trajectories that converge on a single pattern. Children produce less stable movement trajectories, as reflected in higher values of the STI (e.g. Smith & Goffman, 1998), while adults produce more stable movement trajectories as reflected in lower STI values. The STI of lip aperture (a relative distance between upper and lower lips) will be calculated. | through study completion, an average of 3 weeks | |
Primary | The spatiotemporal index (STI) of lip aperture during a neutral valence condition on Day 1 (pretest). | The spatiotemporal index (STI), a measure of speech coordination developed by Smith and colleagues (e.g., Smith, Goffman, Zelaznik, Ying & McGillem, 1995). It will be employed to quantify speech motor control ability and speech motor learning effects. The STI reflects the degree to which repeated performance of a task produces movement trajectories that converge on a single pattern. Children produce less stable movement trajectories, as reflected in higher values of the STI (e.g. Smith & Goffman, 1998), while adults produce more stable movement trajectories as reflected in lower STI values. The STI of lip aperture (a relative distance between upper and lower lips) will be calculated. | through study completion, an average of 3 weeks | |
Primary | The spatiotemporal index (STI) of lip aperture during a negative valence condition on Day 2 (retention). | The spatiotemporal index (STI), a measure of speech coordination developed by Smith and colleagues (e.g., Smith, Goffman, Zelaznik, Ying & McGillem, 1995). It will be employed to quantify speech motor control ability and speech motor learning effects. The STI reflects the degree to which repeated performance of a task produces movement trajectories that converge on a single pattern. Children produce less stable movement trajectories, as reflected in higher values of the STI (e.g. Smith & Goffman, 1998), while adults produce more stable movement trajectories as reflected in lower STI values. The STI of lip aperture (a relative distance between upper and lower lips) will be calculated. | through study completion, an average of 3 weeks | |
Primary | The spatiotemporal index (STI) of lip aperture during a neutral valence condition on Day 2 (retention). | The spatiotemporal index (STI), a measure of speech coordination developed by Smith and colleagues (e.g., Smith, Goffman, Zelaznik, Ying & McGillem, 1995). It will be employed to quantify speech motor control ability and speech motor learning effects. The STI reflects the degree to which repeated performance of a task produces movement trajectories that converge on a single pattern. Children produce less stable movement trajectories, as reflected in higher values of the STI (e.g. Smith & Goffman, 1998), while adults produce more stable movement trajectories as reflected in lower STI values. The STI of lip aperture (a relative distance between upper and lower lips) will be calculated. | through study completion, an average of 3 weeks | |
Secondary | Skin conductance level (SCL) | Skin conductance level (SCL) measures the activity of the sympathetic branch of the autonomic nervous system. Higher SCL during experimental conditions as compared to the baseline is associated with higher sympathetic nervous system activity and provides physiologic validation of the emotional reactivity differences between the experimental conditions. | through study completion, an average of 3 weeks | |
Secondary | Number of phasic skin conductance responses elicited by picture presentations | Phasic skin conductance responses (SCR) measures the activity of the sympathetic branch of the autonomic nervous system. It is elicited by specific stimuli (in this study, by the pictures presented in the two experimental conditions).Greater number of SCRs elicited by picture presentations during experimental conditions is associated with higher sympathetic nervous system activity and provides physiologic validation of the emotional reactivity differences between the experimental conditions. | through study completion, an average of 3 weeks | |
Secondary | Respiratory sinus arrhythmia (RSA) | Respiratory sinus arrhythmia (RSA) (rhythmic fluctuations in heart rate associated with the respiratory cycle) measures the activity of the parasympathetic branch of the autonomic nervous system. Decreased RSA during the experimental conditions as compared to the baseline provides physiologic validation of the emotional reactivity differences between the experimental conditions. | through study completion, an average of 3 weeks | |
Secondary | Executive function (EF) composite score | Executive function skills will be assessed through behavioral tasks using the NIH Toolbox Early Childhood Cognition Battery (Gershon et al., 2013; Zelazo et al., 2013). The tasks include the Flanker Inhibitory Control and Attention Test to examine inhibitory control, Picture Sequence Memory Test to examine episodic memory, and Dimensional Change Card Sort Test to examine mental flexibility and attention. | through study completion, an average of 3 weeks |
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