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Stress Urinary Incontinence clinical trials

View clinical trials related to Stress Urinary Incontinence.

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NCT ID: NCT00565838 Completed - Clinical trials for Stress Urinary Incontinence

Quality-of-Life Outcomes After Autologous Fascial Sling and TVT: a Prospective Randomized Trial

Start date: January 2001
Phase: N/A
Study type: Observational

The objective of the study was to evaluate the impact AFS and TVT procedures on quality-of-life in incontinent women.

NCT ID: NCT00534365 Completed - Clinical trials for Stress Urinary Incontinence

Study Comparing TVT With TVT-SECUR for the Treatment of Stress Urinary Incontinence

SECURiTy
Start date: August 2007
Phase: Phase 3
Study type: Interventional

The purpoe of this study is to compare the safety and efficacy of the tension-free vaginal tape procedure (TVT) to the TVT-SECUR procedure in the treatment of stress urinary incontinence.

NCT ID: NCT00475839 Completed - Clinical trials for Stress Urinary Incontinence

Study Comparing Tension-free Vaginal Tape With the Monarc Procedure for Stress Urinary Incontinence

Start date: December 2004
Phase: Phase 3
Study type: Interventional

Urinary incontinence is a major health issue in women. It is estimated to affect 30 - 40% of older women. Stress urinary incontinence, the most common form of this disease, is treated primarily with surgery. A woman's lifetime risk of surgery for SUI is 4%, with nearly 1/3 of surgery being performed for recurrences. Many different surgical procedures have been described for the treatment of SUI and there is no general agreement as to the most effective. This study compares the safety and efficacy of the tension-free vaginal tape procedure to the Monarc subfascial hammock procedure in the treatment of stress urinary incontinence.

NCT ID: NCT00472069 Completed - Clinical trials for Stress Urinary Incontinence

A New Therapeutic Strategy for Urethral Sphincter Insufficiency

Start date: April 2007
Phase: Phase 1
Study type: Interventional

Stress urinary incontinence is a frequent condition that can be caused by urethral sphincter insufficiency and results in a dramatic deterioration of the quality of life. We developed a new therapeutic strategy for stress urinary incontinence based on the implantation myofibers with their satellite cells in the urethra. The aim of this procedure is to generate functional tissue acting like a new sphincter in the urethra

NCT ID: NCT00463554 Completed - Clinical trials for Stress Urinary Incontinence

TVT-SECUR A Pilot Study for the Treatment of Stress Urinary Incontinence

Start date: April 1, 2006
Phase:
Study type: Observational

The primary objective of this study is to obtain clinical performance information on the GYNECARE TVT-SECUR* System (Tension-free Support for Incontinence) in women with stress urinary incontinence (SUI).

NCT ID: NCT00453739 Completed - Clinical trials for Stress Urinary Incontinence

TVT Worldwide Registry

Start date: February 2007
Phase: N/A
Study type: Observational

The objective of this observational study is to obtain long -term clinical and patient reported outcomes on the use of the GYNECARE family of TVT (Tension-Free Vaginal Tape) systems in women with stress urinary incontinence.

NCT ID: NCT00441454 Completed - Clinical trials for Stress Urinary Incontinence

Retropubic vs. Transobturator Tension-free Vaginal Tape

Start date: September 2004
Phase: N/A
Study type: Interventional

The so-called tension-free vaginal tape (TVT), first described in Sweden in 1996, has become a standard operation worldwide for the treatment of women with stress urinary incontinence. This tape is placed from the vagina behind the pubic bone and exits through the skin of the lower abdomen, just above the pubic bone. In 2001 a urologist in France proposed passing a similar tape laterally (as opposed to behind the pubic bone). This tape is passed through a window of the pelvic bones (the so-called obturator foramen), by what is called a transobturator approach. It is passed through the skin of the thigh (as opposed to the lower abdomen). The reason for this modification was to avoid injuring the bladder and, possibly, provide a more physiologic restoration of the continence mechanism. However, it is unclear whether the lateral (so-called transobturator approach) is as good as or better than the initial approach behind the pubic bone. The purpose of the present study is to compare the standard (retropubic) and the newer (transobturator) approach for the placement of a tape for treating women with stress urinary incontinence.

NCT ID: NCT00271037 Completed - Clinical trials for Pelvic Organ Prolapse

Colpocleisis for Advanced Pelvic Organ Prolapse

Start date: July 2004
Phase: N/A
Study type: Observational

Pelvic organ prolapse occurs when the pelvic organs (e.g., the uterus or bladder) fall or slide down into the vagina. Pelvic organ prolapse can be corrected with surgery. Some types of surgery try to restore the normal anatomy and function of the vagina (i.e., reconstructive surgery). Other surgery repairs the prolapse by essentially closing the vagina (e.g., colpocleisis or colpectomy), thereby leaving a woman unable to have vaginal intercourse in the future. The use of colpocleisis has not been well-studied. The current literature is lacking sufficient studies of colpocleisis to fully understand its risks and benefits for women considering surgery for prolapse. Traditionally, colpocleisis has been restricted to elderly women thought to be poor medical risks for prolonged reconstructive surgery. This study will describe the postoperative course of women who undergo colpocleisis, with particular attention to the persistence or recurrence of urinary incontinence and patient satisfaction after the colpocleisis prolapse surgery.

NCT ID: NCT00270998 Completed - Clinical trials for Urinary Incontinence

ATLAS: Ambulatory Treatments for Leakage Associated With Stress

Start date: June 2005
Phase: Phase 3
Study type: Interventional

Stress urinary incontinence is the uncontrollable leakage of urine with physical effort or stress, such as coughing, sneezing, or exercise. Treatment for stress incontinence can be surgical or non-surgical. Different non-surgical treatments include pelvic muscle exercises and pessary use. Pelvic muscle exercises (often known as "Kegel" exercises) train and strengthen the pelvic muscles and improve incontinence. A pessary is a medical device that fits inside the vagina to give the urethra and bladder extra support and prevent or reduce urinary incontinence. Exercises and pessary use can help women with stress incontinence but it is not known which treatment is better, or if a combination of the two treatments at the same time is best. This study will determine whether pelvic muscle training and exercises, pessary use, or a combination of both exercises and pessary is most effective at improving incontinence in women. The study's primary hypothesis is that pessary use is more effective than pelvic muscle exercises after 3 months of treatment.

NCT ID: NCT00234754 Completed - Clinical trials for Stress Urinary Incontinence

Trans-Obturator Tape Versus Trans-Vaginal Tape for Stress Urinary Incontinence in Women

Start date: September 2005
Phase: N/A
Study type: Interventional

Stress urinary incontinence (SUI) is a health concern for many women. The transvaginal tape (TVT) surgery has become a common procedure to address the problem. Another surgery is now available, trans-obturator tape (TOT). The investigators will compare these 2 approaches to dealing with SUI and follow the women for 1 year. Women will also be followed at 5 years after surgery.