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Streptococcal Infections clinical trials

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NCT ID: NCT01577108 Recruiting - Clinical trials for Group B Streptococcal Infection

Oral Probiotics Reduce Group B Streptococci Colonization in Pregnant Women

Start date: April 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to examine whether daily use of oral gelatin capsules containing dried viable Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 can reduce the GBS colonization rate of vagina and rectum in pregnant women who present with GBS-positive diagnosed by GBS culture at 35-37 weeks gestation. This study is a prospective double blind randomized clinical trial. Vaginal and rectal GBS screening culture are carried out for all pregnant women at 35-37 weeks of gestation in our out-patient department. Subjects with vagina and rectum GBS colonization are invited to participate in our study after informed consent. A total of 200 pregnant women will participate in the study during the 12-months trial period. They are randomly assigned to one of the two groups. The study group is treated with two oral capsules of probiotics once daily (before sleeping) for 14 days, and the control group will take 2 capsules of placebos. Vaginal and rectal GBS culture is repeated for all participators 2 weeks later. All participators will treated according to GBS guideline by CDC in 2002 during laboring.

NCT ID: NCT01491776 Recruiting - Strep Throat Clinical Trials

Evaluation of the IND One Step Strep A Rapid Test vs. Culture

Start date: December 2011
Phase: N/A
Study type: Observational

The purpose of this study is to demonstrate the ability of the IND One Step Strep A test to accurately test a throat swab specimen from a symptomatic patient for the presence or absence of Group A Streptococcus (Strep A) when compared to culture.