Clinical Trials Logo

Clinical Trial Summary

Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus. Three types of subects will be enrolled: (1) Families with at least 3 members with strabismus, (2) individuals with infantile esotropia and their parents and siblings, and (3) individuals with infantile nystagmus and their parents. Whole exome and/or whole genome sequencing will be used to identify genetic variants shared by family members with strabismus and to identify genetic causes of nystagmus.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04770519
Study type Observational
Source Boston Children's Hospital
Contact Tapiwa Muvavarirwa, BA
Phone 857-292-3768
Email research.whitman@childrens.harvard.edu
Status Recruiting
Phase
Start date September 3, 2021
Completion date December 2026

See also
  Status Clinical Trial Phase
Completed NCT03596138 - Reliability and Reproducibility of Automated Angular Measurement in Strabismus
Completed NCT04432181 - Comparison of Deviation Types Among Astigmatic Children With Or Without Amblyopia
Recruiting NCT03713268 - Intraoperative OCT Guidance of Intraocular Surgery II
Completed NCT01512355 - The Effect of Dexmedetomidine on Decreasing Emergence Agitation and Delirium in Pediatric Patients Undergoing Strabismus Surgery N/A
Completed NCT00461656 - Povidone-iodine Antisepsis for Strabismus Surgery Phase 4
Completed NCT00535938 - MDs on Botox Utility (MOBILITY) N/A
Completed NCT01109459 - Multimodal Physician Intervention to Detect Amblyopia N/A
Not yet recruiting NCT06035757 - The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery Phase 4
Completed NCT01430247 - Vision Screening for the Detection of Amblyopia N/A
Recruiting NCT04416776 - Validation of the Utility of Strabismus Intelligent Diagnostic System
Recruiting NCT04353960 - The Alaska Oculocardiac Reflex Study
Terminated NCT02246556 - Dichoptic Virtual Reality Therapy for Amblyopia in Adults Phase 1
Completed NCT01726842 - Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner N/A
Completed NCT00001143 - Development of the Eye Motor System During the First 7 Months of Life in Infants With and Without a Family History of Cross-Eye N/A
Completed NCT04303832 - Exercise Interventions of Eye Muscles Post Strabismus Surgery N/A
Completed NCT03806270 - Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery
Recruiting NCT05425589 - Adjustable Strabismus Surgery N/A
Completed NCT00559234 - Potential Research Participants for Future Studies of Inherited Eye Diseases N/A
Completed NCT02570555 - Strabismus Surgery and Driving Ability
Completed NCT02360969 - Effect of Neuromuscular Blockade on the Oculomotor by Not Squinting Child N/A