Effectiveness Evaluation in Thrombus Aspiration in Patients With STEMI and High Thrombotic Load

STEMI Clinical Trial

Official title:

Effectiveness Evaluation in Thrombus Aspiration in Patients With STEMI and High Thrombotic Load

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT05043597
• Other study ID #: LHD Thrombus aspiration
• Status: Active, not recruiting
• Phase: N/A
• Start date: March 1, 2020
• Est. completion date: February 28, 2023

Study information

• Verified date: September 2021
• Source: Shenzhen People's Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study intends to evaluate thrombus on the basis of different methods for evaluating thrombus load The effect of aspiration on the prognosis of STEMI patients with high thrombotic load Provide a basis for the standardized use of aspiration; at the same time, discover the best benefit groups for thrombus aspiration

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 3838
• Est. completion date: February 28, 2023
• Est. primary completion date: January 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• (1) Age = 18 years; (2) Voluntary signing of informed consent; (3) Onset of 12 hours STEMI patients who underwent PCI reperfusion therapy within time; (4) The guidewire passes through the lesion and the blood Heavy embolism load (TIMI thrombus classification = 3).

Exclusion Criteria:

• (1) Hemodynamics is unstable or there is cardiogenic shock; (2) After thrombolytic therapy; (3) The expected survival time is less than 6 months due to non-cardiac diseases; (4) Past trips Coronary artery bypass graft patients; (5) Participate in other drug and device research within 30 days; (6) Before surgery, clear active gastrointestinal bleeding or other contraindications for taking dual antiplatelet drugs (7) Patients deemed unsuitable for enrollment by other researchers

Related Conditions & MeSH terms

• ST Elevation Myocardial Infarction
• STEMI

Intervention

Procedure:
• Thrombus aspiration
Thrombus aspiration

Locations

Country	Name	City	State
China	Shenzhen People's Hospital	Shenzhen

Sponsors (1)

Lead Sponsor	Collaborator
Shenzhen People's Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Adverse cardiovascular events	Including cardiogenic death, recurring myocardial infarction Stent thrombosis or target vessel revascularization	3 years