Safety, Tolerability, and Efficacy of Enteral Nutrition Versus Paranteral Nutrition in Hematopoietic Stem Cell Transplant Patients: A Pilot Randomized Controlled Study

Stem Cell Clinical Trial

Official title: Safety, Tolerability, and Efficacy of Enteral Nutrition Versus Paranteral Nutrition in Hematopoietic Stem Cell Transplant Patients: A Pilot Randomized Controlled Study

Status Recruiting

Clinical Trial Summary

The goal of this research study is to learn if feeding someone after a stem cell transplant is safe and practical.

Clinical Trial Description

Primary Objective:

a. To determine feasibility of administering enteral nutrition (EN) via NG/GT in SCT population in peri-transplant period.

Secondary Objectives:

1. Determine the differential effects of enteral feeding versus Parenteral feeding on nutrition, and quality of life.

2. Determine the differential effects of enteral feeding versus parenteral feeding on survival and, medical comorbidities

3. Determine the differential effects of enteral feeding versus parenteral feeding on Fitbit data study for patients co-enrolled in Pediatric Energy Balance Data Repository Protocol PA18-0130.

4. Identify differential effects on microbiome for patients co-enrolled on "A Study to Collect Peripheral Blood, Tissue, and Bone Marrow samples from Donors and Recipients of blood and marrow transplants for Laboratory Research Protocol Lab99-062".

5. Determine adverse effects of enteral feeding in this population ;

Related Conditions & MeSH terms

• Stem Cell

• NCT number: NCT06004063
• Study type: Interventional
• Source: M.D. Anderson Cancer Center
• Contact: Shehla Razvi, MD
• Phone: (713) 792-6635
• Email: srazvi@mdanderson.org
• Status: Recruiting
• Phase: N/A
• Start date: August 4, 2023
• Completion date: December 31, 2029