Trial of Terbutaline for the Treatment of Status Asthmaticus in Children

Status Completed

Clinical Trial Summary

Although widely used for the treatment of pediatric status asthmaticus, intravenous terbutaline has potentially significant side effects; may not improve outcomes; and may increase Intensive Care Unit (ICU) length of stay. This study is designed to test the efficacy of intravenous terbutaline for the treatment of status asthmaticus by adding intravenous terbutaline or placebo to standard asthma treatment. The dose of terbutaline or placebo will be titrated according to severity of illness as quantified by a validated clinical asthma score. Differences in outcomes between the study groups, such as length of stay, hospital costs, and lung function will be compared.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Status Asthmaticus

Clinical Trial Details

NCT number	NCT00124995
Study type	Interventional
Source	Connecticut Children's Medical Center
Contact
Status	Completed
Phase	Phase 4
Start date	October 2003
Completion date	October 2006

View Details

See also
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