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Clinical Trial Summary

The purpose of this study is to see if the IRX-2 regimen and Durvalumab, will have a tolerable safety profile and will increase the intratumoral immune profile compared with the pretreatment tumors.


Clinical Trial Description

Study Population: Patients with histologically or cytologically confirmed recurrent or metastatic squamous cell carcinoma of oral cavity, oropharynx, paranasal sinuses, hypopharynx, or larynx that is not amenable to local therapy with curative intent. Squamous cell carcinoma of unknown primary in cervical lymph node can be included only if p16 status is positive. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03381183
Study type Interventional
Source H. Lee Moffitt Cancer Center and Research Institute
Contact
Status Active, not recruiting
Phase Phase 1
Start date August 21, 2019
Completion date December 2024

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