The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance

Sports Clinical Trial

Official title:

The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04292106
• Other study ID #: 092619
• Status: Completed
• Phase: N/A
• Start date: September 26, 2019
• Est. completion date: March 30, 2020

Study information

• Verified date: January 2022
• Source: Lipscomb University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Red Spinach is a natural food which is a rich source of nitrates, which are beneficial in hemodynamics, cardiovascular function, and have natural hypotensive and antianginal effects. Red spinach extract has been shown to be beneficial in exercise performance, albeit mostly in aerobic exercise. In a previous study in our lab, we found that dietary nitrate consumption resulted in significantly greater isometric force production in teenage males. However, currently there is little know regarding the effects of dietary nitrate supplementation on isometric strength, resistance exercise and cognitive performance.

Description:

This research study is designed to measure the effects of red spinach extract (RSE) on markers of physical and cognitive performance during and following anaerobic exercise.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 11
• Est. completion date: March 30, 2020
• Est. primary completion date: March 30, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 34 Years

Eligibility

Inclusion Criteria:

• 18-34 years old Participants must have at least 1 year of resistance training experience.
• Free of any physical limitations, medications, and supplements that may affect performance, as determined by a health and activity questionnaire.
• Are free of musculoskeletal injuries
• Are not taking medications that may interfere with study measurements

Exclusion Criteria:

• Participants that cannot take either the RSE or placebo supplement will be excluded, as this will be a double-blind study.
• Furthermore, participants that cannot participate in pre- and post-research testing, and/or those that cannot commit to regular training sessions will be excluded.
• Inability to perform physical exercise (determined by health and activity questionnaire)
• Taking any other nutritional supplement or performance enhancing drug.
• Any chronic illness that causes continuous medical care

Related Conditions & MeSH terms

• Sports

Intervention

Dietary Supplement:
• Red Spinach Extract (RSE)
Oral capsules containing 2g of Red Spinach Extract will be consumed daily for 7 days
• Placebo
Oral placebo capsules will be taken consisting of maltodrextrin daily for 7 days

Locations

Country	Name	City	State
United States	Jeremy Townsend	Nashville	Tennessee

Sponsors (1)

Lead Sponsor	Collaborator
Lipscomb University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Bench Press Repetitions to Fatiuge	Number of repetitions completed in each set during the acute exercise bout will be recorded and analyzed	Through study completion, during both treatments (~4 weeks)
Primary	Bench Press Power	Power during bench press repetitions will be measured via a linear transducer.	Through study completion, during both treatments (~4 weeks)
Primary	Isometric Mid-thigh pull (IMTP) Peak Force	Peak Force will be measured via dual force plates during a full-body isometric strength test.	Through study completion, during both treatments (~4 weeks)
Primary	Isometric Mid-thigh pull (IMTP) Rate of Force Development	Rate of Force development will be measured via dual force plates during a full-body isometric strength test.	Through study completion, during both treatments (~4 weeks)
Secondary	Estimated Muscle Blood Flow via Near-infrared Spectroscopy (NIRS)	Measures of muscle oxygenation of the anterior deltoid will be estimated using a NIRS Device.	Through study completion, during both treatments (~4 weeks)
Secondary	Cognitive Performance via Stroop Test	The Stroop Color and Word Test (SCWT) is a neuropsychological test used to assess cognitive performance. This will be administered before and after the fatiguing bench press protocol	Through study completion, during both treatments (~4 weeks)