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Spondylitis clinical trials

View clinical trials related to Spondylitis.

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NCT ID: NCT06432530 Completed - Clinical trials for Brucella Spondylitis

Can Hematological Inflammatory Indexes be Used to Differentiate Type 1 Modic Changes From Brucella Spondylodiscitis

Start date: January 9, 2023
Phase:
Study type: Observational

Hematological inflammatory indices (Table 2) are currently very popular and have diagnostic, prognostic, and predictive, roles in various diseases. Considering their promising roles, we hypothesized that hematological inflammatory indices may have a distinctive value between brucella spondylodiscitis and type 1 Modic Changes (MCs). If the hypothesis is valid, early diagnosis-differential diagnosis-treatment processes may become easier and more successful. Given that hematological inflammatory indices are faster, practical, simpler, inexpensive, and easily accessible indicators, they may be more appropriate tools in differentiation between brucella spondylodiscitis and type 1 MCs.

NCT ID: NCT06310057 Completed - Clinical trials for Axial Spondyloarthritis

Tofacitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Dose Escalation Study

Start date: January 1, 2022
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to assess the efficacy of tofacitinib in refractory axial spodyloarthritis (ax-SpA) with dose escalation from 10mg to 15mg. Patients will start on 10mg and then divided into 2 groups (10 and 15) at 3rd month according to major improvement criteria. The main question[s] it aims to answer are: - Efficacy and safety of tofacitinib in different doses - If escalation of tofacitinib is justified if clinical criteria is not fulfilled at 10mg

NCT ID: NCT06252064 Completed - Spondyloarthropathy Clinical Trials

Rehabilitative Therapy and Pridinol in Patients With Lumbar Spondylarthrosis and Chronic Low Back Pain

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Spondyloarthrosis is a degenerative disease involving the intervertebral disc, vertebral bodies, and adjacent soft tissues. Treatment aims to slow disease progression and manage symptoms through an interdisciplinary approach.It can be conservative, pharmacological and interventional, rarely chirurgic. This study aimed to evaluate the effectiveness of a rehabilitation program combined with Pridinol Mesylate in the treatment of Spondyloarthrosis in elderly patients in terms of pain resolution, improving disability, and quality of life versus single treatment. A randomized controlled trial was conducted in patients with spondyloarthritis. The patients recruited were divided into three groups: the Combined Group (CG), who received a rehabilitation program combined with Pridinol Mesylate; the Rehabilitation Group (RG), who received only the same rehabilitation program; and the Drug Group (DG), who received only the administration of the drug.

NCT ID: NCT06230952 Completed - Clinical trials for Axial Spondyloarthritis

Reliability of BASDAI and BASFI Applied by Tele-Assessment Method in Axial SpA Spondyloarthritis

Start date: February 8, 2024
Phase:
Study type: Observational

The goal of this observational study is to investigate the reliability of BASDAI and BASFI questionnaires applied via tele-assessment in axial spondyloarthritis patients.

NCT ID: NCT06226792 Completed - Clinical trials for Ankylosing Spondylitis

Muscle Architecture in Ankylosing Spondylitis

Start date: January 18, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to determine whether there is a decrease in muscle mass and the relationship between lower extremity skeletal muscle mass, muscle strength and disease activity in Ankylosing spondylitis. The main questions it aims to answer are: - Is there a relationship between the muscle thickness and pennation angle of the quadriceps, Gastrocnemius medialis and lateralis, Vastus medialis and lateralis and tibialis anterior muscles with disease activity and muscle strength? - Are there any differences in the results of morphological parameters of lower extremity muscles between Ankylosing spondylitis and voluntary participants? Researchers will compare voluntary participants to see if any difference in lower muscle morphological parameters.

NCT ID: NCT06185712 Completed - Clinical trials for Ankylosing Spondylitis

Patient Education in Ankylosing Spondylitis

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

This study was carried out to investigate the effect of a nurse-led disease management education program in AS on patient compliance, disease activity, functional capacity, kinesiophobia, and quality of life. A total of 122 patients diagnosed with AS according to the modified New York criteria were included in the study. The intervention group received nurse-led individualized disease management education. In the control group, no interventions were performed other than routine clinical procedures.

NCT ID: NCT06094686 Completed - Clinical trials for Ankylosing Spondylitis

Epicardial Adipose Tissue Thickness and the Related Factors in Patients With Ankylosing Spondylitis

Start date: August 1, 2015
Phase:
Study type: Observational

The aim of this study was to assess the EATT and the related factors in patients with AS and to compare the results with that of the healthy controls'

NCT ID: NCT06094673 Completed - Clinical trials for Ankylosing Spondylitis

The Relationship Between Systemic Immune Inflammation Index and Disease Activity in Patients With Ankylosing Spondylitis

Start date: June 1, 2023
Phase:
Study type: Observational [Patient Registry]

In this study, the aim was to investigate the relationship between SII and other laboratory parameters with disease activity in AS patients and to discuss its usability in the follow-up and treatment process.

NCT ID: NCT06085534 Completed - Clinical trials for Ankylosing Spondylitis

A Study of LNK01001 Capsule in Patients With Ankylosing Spondylitis

Start date: January 6, 2022
Phase: Phase 2
Study type: Interventional

The objective of this study was to evaluate the safety and efficacy of multiple doses of LNK01001 monotherapy versus placebo in the treatment of adults with active Ankylosing Spondylitis

NCT ID: NCT05987111 Completed - Clinical trials for Ankylosing Spondylitis

Pilates in Ankylosing Spondylitis

Start date: August 2, 2022
Phase: N/A
Study type: Interventional

This study was planned to examine and compare the effectiveness of two different pilates exercise methods (mat pilates vs reformer pilates) in individuals with Ankylosing Spondylitis(AS).