Clinical Trials Logo

Spinal Stenosis clinical trials

View clinical trials related to Spinal Stenosis.

Filter by:

NCT ID: NCT06060821 Completed - Spinal Stenosis Clinical Trials

Validity and Reliability of the 2-minute Step Test in Patients With Lumbar Spinal Stenosis

Start date: September 1, 2023
Phase:
Study type: Observational [Patient Registry]

The aim of this study was to investigate the validity and reliability of the 2 Minute Step Test (2MST) in patients with symptomatic degenerative lumbar spinal stenosis and to explore its correlation with objective assessment methods, namely the 2 Minute Walk Test (2MWT) and the 6 Minute Walk Test (6MWT).

NCT ID: NCT06058143 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Crenel Lateral Interbody Fusion Combined With Lateral Plate Fixation for LSS Combined With Lumbar Instability

Start date: November 2023
Phase: N/A
Study type: Interventional

At present, interbody fusion is the mainstream treatment for patients with lumbar spinal stenosis (LSS) and lumbar instability. However, the choice of interbody fusion for LSS patients with lumbar instability remains controversial. Recently, we developed crenel lateral interbody fusion combined with lateral plate fixation(CLIF - LP) for patients with LSS and lumbar instability. This surgical method has many advantages and showed good results for patients with LSS and lumbar instability. Therefore, we propose the following hypothesis: The clinical and imaging efficacy of CLIF-LP in the treatment of LSS patients with lumbar instability is not inferior to that of traditional transforaminal lumber interbody fusion (TLIF).

NCT ID: NCT06057428 Recruiting - Clinical trials for Lumbar Spinal Stenosis

Activity Levels Amongst Patients With Lumbar Spinal Stenosis

B-ATLAS
Start date: September 21, 2023
Phase:
Study type: Observational

Lumbar spinal stenosis (LSS) is one of the most common degenerative diseases of the spinal column, with symptoms including low back pain which worsens with ambulation, poor balance, decreased activity due to pain, and a marked decrease in quality of life (QoL). Prevalence rises with age, and current treatment options range from varied conservative management strategies, to surgical intervention with decompression of neural structures. While the effects of surgical decompression on back pain and QoL has been widely researched, the effects of surgery on activity levels is less well understood. Though patients generally have subjective improvements in this parameter after surgery, objective measurements in this patient group have been lacking. This study aims to investigate the effects of decompressive surgery on activity levels in elderly patients with LSS. Measurements of activity will be taken before and after decompressive surgery, as well as with regular intervals during a two-year follow-up period. A better understanding of the effect that LSS has on activity may lead to more patients being able to receive surgical treatment, which is hypothesized to lead to an increase in QoL and less perceived disability amongst this patient group.

NCT ID: NCT06034405 Recruiting - Clinical trials for Lumbar Spinal Stenosis

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Start date: September 19, 2023
Phase:
Study type: Observational

Primary objective: To identify older adults with transthyretin cardiac amyloidosis (ATTR-CA) early in the course of the illness, at a time when disease modifying therapies are most effective. The specific aims of this epidemiologic investigation include: 1. To identify subjects with previous lumbar spinal stenosis (LSS) Surgery who have evidence of transthyretin (TTR) amyloid deposits in spinal specimens and could be at risk for ATTR cardiac amyloidosis. 2. To evaluate for ATTR-CA among those with localized TTR in the spinal tissue. The study will also explore the following: 1. The prevalence of amyloid in lumbar spinal stenosis specimens by Congo Red staining. 2. The prevalence of TTR deposits among subjects with amyloid as determined by mass spectrometry. 3. Evaluation of a novel artificial intelligence technique for that can identify amyloid histologically with standard H&E staining. 4. Difference in ATTR-CA prevalence between subjects with TTR and indeterminate amyloid deposits in subject's spine by myocardial uptake of technetium pyrophosphate scan (Tc99-PYP).

NCT ID: NCT06024785 Not yet recruiting - Spinal Stenosis Clinical Trials

Vertebropexy - Randomized-controlled Trial

VPRCT
Start date: September 2024
Phase: N/A
Study type: Interventional

To assess the need for additional fusion surgery versus the risk of a revision surgery in patients with degenerative lumbar spinal disease and to assess efficacy and risk of the ligamentous fixation technique (vertebropexy)

NCT ID: NCT06023498 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Optimizing Impact of Manual Therapy on Lumbar Spinal Stenosis

Start date: July 2024
Phase: N/A
Study type: Interventional

Lumbar spinal stenosis, a common condition in older adults, can cause pain and difficulty walking (i.e., intermittent neurogenic claudication - INC). Patients with INC not infrequently undergo spinal surgery that fails to help them 1/3-1/2 the time. The purpose of this multi-site feasibility study is to prepare for the conduct of a randomized controlled trial to test the efficacy of manual therapy, exercise, and intramuscular electroacupuncture in reducing pain and improving walking ability for those with INC, and ultimately limiting the need for surgical referrals.

NCT ID: NCT06000319 Not yet recruiting - Clinical trials for Degenerative Disc Disease

Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion

Start date: September 2023
Phase:
Study type: Observational

The aim of this study is to evaluate the effectiveness and safety of Natural Matrix Protein™ (NMP™) fibers when used in cervical or lumbar interbody fusion in patients with degenerative disc disease (DDD), spinal stenosis, spondylolisthesis undergoing cervical or lumbar interbody spine fusion at no more than 3 adjacent levels.

NCT ID: NCT05963815 Recruiting - Spinal Stenosis Clinical Trials

The Spine PROMCO Study

Spine PROMCO
Start date: January 13, 2023
Phase:
Study type: Observational

Our primary objective is to design a cohort to determine the treatment outcome of different surgical interventions of the degenerative lumbar spine highlighting the expediency and value of the current surgical treatment program.

NCT ID: NCT05959343 Completed - Clinical trials for Lumbar Spinal Stenosis

Enhanced Recovery After Surgery in Oblique Lumbar Interbody Fusion

Start date: July 12, 2023
Phase: N/A
Study type: Interventional

This study is a randomized controlled non-inferiority trial designed to evaluate the impact of implementing the 'Early Recovery After Surgery Clinical Pathway (ERAS CP)' on patient-reported pain levels at the time of discharge following Oblique Lumbar Interbody Fusion (OLIF) surgery

NCT ID: NCT05895968 Recruiting - Clinical trials for Cervical Spinal Stenosis

Researching the Useful of Barb Suture in Obese Patients Undergoing Posterior Cervical Surgery

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Through a single-center, exploratory clinical study, the safety and effectiveness of using barb wire in the incision and suture of posterior cervical surgery in obese patients were evaluated, providing a basis for its wide clinical application in posterior cervical surgery.