Clinical Trials Logo

Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT04586790
Other study ID # oral vasopressors
Secondary ID
Status Recruiting
Phase Phase 2
First received
Last updated
Start date October 15, 2020
Est. completion date January 28, 2021

Study information

Verified date October 2020
Source Assiut University
Contact Ahmed T Ahmed, lecture
Phone 01062716629
Email Ahmedtalaat_ahmed@yahoo.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

the study is developed to evaluate the effect of use of oral vasopressors (midodrine versus minirin) on weaning ICU patients from IV vasopressors (noradrenaline) and compare between them for efficacy in shortage the duration of IV vasopressor and has low complications and side effects.


Recruitment information / eligibility

Status Recruiting
Enrollment 90
Est. completion date January 28, 2021
Est. primary completion date January 1, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria:

- Age of 18 - 60 years.

- Patients of both genders.

- Patients diagnosed by spinal shock and they are in the recovery stage .

Exclusion Criteria:

- Patient refusal.

- Anuric or oliguric patients or patients with chronic kidney disease.

- Patients with allergy to medication included in the study.

Study Design


Related Conditions & MeSH terms


Intervention

Drug:
Midodrine Oral Tablet
midodrine group will receive midodrine 10 mg PO q 8 hr with gradual weaning of IV nor-adrenaline after receiving 4 doses of oral midodrine .
Minirin oral tablet
Minirin group will receive minirin 60 µg PO q 8 hr with gradual weaning of IV nor-adrenaline after receiving 4 doses of oral minirin .
Nor-Adrenaline
control group will receive IV nor-adrenaline and is gradually weaning from it according to routine hospital care without adding oral midodrine or oral minirin .

Locations

Country Name City State
Egypt Ahmed Talaat Ahmed Assiut

Sponsors (1)

Lead Sponsor Collaborator
Ahmed talaat ahmed aly

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary liberation the patient from IV vasopressors with maintaining hemodynamics. Blood pressure will be assessed regularly every 15 minutes 48 hrs
See also
  Status Clinical Trial Phase
Recruiting NCT05637645 - Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section N/A
Withdrawn NCT05207826 - Detrusor Activity Recovery in Acute Traumatic Spinal Cord Injuries