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Conventional With Stereotactic Radiotherapy for Pain Reduction and Quality of Life in Spinal Metastases — RACOST  

Spinal Metastases Clinical Trial

Official title:
A RAndomized Trial Comparing COnventional With STereotactic Radiotherapy for Pain Reduction and Quality of Life in Spinal Metastases (RACOST-trial)

Clinical Trial Summary

A randomized, multicentre, phase III study comparing conventional radiotherapy (1x8Gy) with stereotactic radiotherapy (1x20Gy) for pain reduction and quality of life in spinal metastases.

Clinical Trial Description

Study population: patients with painful spinal metastases from solid tumors without spinal cord compression or cord instability. Objective: This study will test the hypothesis that stereotactic radiotherapy gives a better and longer lasting reduction of pain, local control and therewith a better quality of life. This in order to optimize and to individualize the treatment options for the patient. Study design: Complaints due to pain will be analysed using the validated Dutch Brief Pain Inventory (BPI) and side-effects will be recorded using the Common Toxicity Criteria for Adverse Events (CTCAE). In addition to this the quality of life will be analysed using the EORTC QOL-C15-PAL and EORTC QLQ-BM22 questionnaires. For analysis of cost-effectiveness the EQ-5D will be used. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02407795
Study type Interventional
Source Radboud University Medical Center
Contact
Status Terminated
Phase N/A
Start date May 2015
Completion date November 10, 2021
View Details
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