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NCT03492372 Clinical Trial

Molecular Characterization of Spinal Tissue

Spinal Diseases Clinical Trial

Official title:
Molecular Characterization of Spinal Tissue

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT03492372
Other study ID # 14-008177
Secondary ID
Status Enrolling by invitation
Phase
First received
Last updated
Start date March 31, 2015
Est. completion date July 2025

Study information
Verified date August 2023
Source Mayo Clinic
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The researchers are trying to identify molecular mechanisms that control spine deformity and degenerative changes that can be used for therapeutic strategies.

Description:

Discarded surgical material from spinal procedures is collected. RNA analysis and other tests on the tissue is performed to determine markers of pathologic disease and to develop pharmacologic treatment strategies for pediatric spinal disorders.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 300
Est. completion date July 2025
Est. primary completion date July 2025
Accepts healthy volunteers No
Gender All
Age group 1 Year to 80 Years
Eligibility Inclusion Criteria: - Children and adults undergoing surgical procedures where spinal tissues are removed as a normal part of their procedure. Material from adults may be collected as a control group. Exclusion Criteria: - Surgeries where spinal tissues are not being removed.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Waste tissues are collected at the time of spinal surgery.
This is a single visit study. Waste tissues are collected at the time of spinal surgery.

Locations
Country Name City State
United States Mayo Clinic Rochester Minnesota

Sponsors (1)
Lead Sponsor Collaborator
Mayo Clinic

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary RNA expression Measure RNA levels in spinal tissues samples (ng/mL) Baseline
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