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Autologous Bone Marrow-derived Mononuclear Cells for Acute Spinal Cord Injury

Spinal Cord Injury Clinical Trial

Official title:
Intrathecal Transplantation of Autologous Bone Marrow-derived Mononuclear Cells for Treating Traumatic Acute Spinal Cord Injury

Clinical Trial Summary

The purpose of this study is to evaluate the safety and effectiveness of intrathecal transplantation of autologous bone marrow-derived mononuclear cells for the treatment of traumatic acute spinal cord injury. Spinal cord injury can be divided into three phases, which are acute (within 2 weeks), sub-acute (2 weeks to 6 months), and chronic (over 6 months). Early treatment is the key to improve the prognosis, however, the majority of clinic trails nowadays are focusing on sub-acute or chronic phase because it takes 4-6 weeks to expand the autologous stem cells. In this study, the investigators will treat patients with acute spinal cord injury with autologous bone marrow-derived mononuclear cells and compare with the control group.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04528550
Study type Interventional
Source Shanghai Changzheng Hospital
Contact Xuhua Lu, M.D.
Phone 86-21-81885793
Email xuhualu@hotmail.com
Status Recruiting
Phase Phase 2
Start date October 1, 2020
Completion date December 1, 2023
View Details
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