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Recovery of Cardiovascular Function With Epidural Stimulation After Human Spinal Cord Injury

Spinal Cord Injury Clinical Trial

Official title:
Recovery of Cardiovascular Function With Epidural Stimulation After Human Spinal Cord Injury

Clinical Trial Summary

We propose to demonstrate that epidural stimulation (ES) can be used to recover significant levels of autonomic control of cardiovascular and respiratory function as well as the ability to voluntarily control leg movements below the injury level. This intervention would provide an immediate therapeutic alternative to individuals who now have no recourse for treatment.

Clinical Trial Description

We will enroll 4 research participants who have sustained a motor complete SCI to participate in the proposed experiments. Participants will be screened for eligibility, followed by 80 days of usual care, epidural implantation, 80 days of cardiovascular epidural stimulation training, 80 days of voluntary movement (VM) epidural stimulation training and finally 80 days of stand epidural stimulation training. These interventions are done in sequential order, however they are cumulative. In between each intervention, participants will undergo motor and cardiovascular experiments and assessments. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02037620
Study type Interventional
Source University of Louisville
Contact
Status Completed
Phase N/A
Start date July 2014
Completion date September 20, 2019
View Details
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