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Spina Bifida clinical trials

View clinical trials related to Spina Bifida.

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NCT ID: NCT03090633 Active, not recruiting - Spina Bifida Clinical Trials

Fetoscopic Repair of Isolated Fetal Spina Bifida

Start date: May 11, 2017
Phase: N/A
Study type: Interventional

The purpose of this investigation is to evaluate maternal and fetal outcomes following fetoscopic repair of fetal spina bifida at the Johns Hopkins Hospital. The hypothesis of this study is that fetoscopic spina bifida repair is feasible and has the same effectiveness as open repair of fetal spina bifida, but with the benefit of significantly lower maternal and fetal complication rates. The fetal benefit of the procedure will be the prenatal repair of spina bifida. The maternal benefit of fetoscopic spina bifida repair will be the avoidance of a large uterine incision. This type of incision increases the risk of uterine rupture and requires that all future deliveries are by cesarean section. The use of the minimally invasive fetoscopic surgical technique may also lower the risk of preterm premature rupture of membranes and preterm birth compared to open fetal surgery. Finally, successful fetoscopic spina bifida repair also makes vaginal delivery possible.

NCT ID: NCT00891891 Active, not recruiting - Spina Bifida Clinical Trials

Psychosocial Adjustment of Adolescents With Spina Bifida

CHATS
Start date: September 2005
Phase:
Study type: Observational

The purpose of this longitudinal study is to evaluate a developmentally-oriented bio-neuropsychological model of adjustment in youth and young adults with spina bifida. The theoretical framework for the study is a developmentally-oriented bio-neuropsychosocial model of psychological adjustment.

NCT ID: NCT00031122 Active, not recruiting - Spina Bifida Clinical Trials

Study of Genetic Risk Factors for Spina Bifida and Anencephaly

SBRR
Start date: September 2000
Phase: N/A
Study type: Observational

The purpose of this study is to describe the genetic contribution to the neural tube defects spina bifida (SB) and anencephaly (A), which includes identifying patients, defining the roles of certain genes, and studying gene-environment interactions.