Clinical Trials Logo
  1. Home
  2. Speech
  3. NCT05723575

Modulation of Sensory Acuity With Transcranial Magnetic Stimulation (TMS)

Speech Clinical Trial

Official title:
Behavioral and Neural Measures of Speech Motor Control

Clinical Trial Summary

The purpose of this research study is to understand how the brain processes and controls speech in healthy people. The investigators are doing this research because it will help identify the mechanisms that allow people to perceive their own speech errors and to learn new speech sounds, which may be applied to people who have communication disorders. 15 participants will be enrolled into this part of the study and can expect to be on study for 4 visits of 2-4 hours each.

Clinical Trial Description

The overall study (Establishing the clinical utility of sensorimotor adaptation for speech rehabilitation) aims to understand how cognitive, perceptual, and motor processes are integrated in the control of speech movements. The investigators study how this complex skill is performed in healthy speakers to understand how this system functions, how this skill relates to the perception of speech, and what role different parts of the brain play in this process. Different studies look at how speech motor control is executed, maintained, and changed. Overall, the study will recruit 329 participants over the course of 5 years. Participants can expect to be on study for up to 3 weeks. The entire study is composed of 8 experiments and 6 interventions. The present record represents the experiments involving transcranial magnetic stimulation (TMS), i.e. Experiment 7: Using TMS to alter somatosensory acuity. This paradigm uses theta-burst transcranial magnetic stimulation (tbTMS) to modulate the excitability of sensory cortices to examine the effect on sensory acuity and sensorimotor adaptation. Participants will complete three total sessions targeting primary somatosensory cortex (S1): one using intermittent theta-burst stimulation (iTBS), one using continuous theta-burst stimulation (cTBS), and one with sham stimulation. The effect of the stimulation on auditory acuity will be measured through a tactile discrimination task in which participants report the relative amplitude and/or timing of vibrating probes pressed lightly into the tongue using a custom device (a version of the Corticalmetrics Brain Gauge adapted to study the orofacial system). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05723575
Study type Interventional
Source University of Wisconsin, Madison
Contact
Status Completed
Phase N/A
Start date November 18, 2022
Completion date May 26, 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT06053190 - Effects of Clear Speech on Listening Effort and Memory in Sentence Processing N/A
Completed NCT04547569 - Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning N/A
Completed NCT05286658 - Behavioral and Neural Responses to External Alterations of Speech Variability N/A
Recruiting NCT05634356 - Social Influences on Sensorimotor Integration of Speech Production and Perception During Early Vocal Learning N/A
Completed NCT05635929 - Oral Mucositis and Quality of Life With a Mucosa Topical Composition in Head & Neck Cancer Patients. N/A
Recruiting NCT03504514 - Evaluation of the Effect of a Speech Detection Tool on the Improvement of Phonation in Neuromuscular Patients Dependent on Mechanical Ventilation N/A
Completed NCT04010500 - Speech Performance of Rugby Players When Using Different Types of Mouthguard N/A
Completed NCT05256095 - Thinking in Speech for Children With Autism N/A
Not yet recruiting NCT06467292 - Speech Motor Learning and Retention (Master Protocol) N/A
Not yet recruiting NCT06467305 - Speech Motor Learning and Retention (Aim 1) N/A
Recruiting NCT02753192 - Dysarthria in Parkinson's Disease: Lusophony vs. Francophony Comparison N/A
Active, not recruiting NCT04273672 - Speech, Linguistic and Acoustic Markers in Parkinson's Disease
Recruiting NCT06164717 - Behavioral and Neural Characteristics of Adaptive Speech Motor Control N/A
Completed NCT03008174 - Early Speech With One-Way Speaking Valve in Tracheostomy Patients N/A
Recruiting NCT06168695 - Impact of Anterior Cross Bite Treatment on Children's Speech Performance N/A
Recruiting NCT06233513 - Vowel Space Expansion Sensorimotor Adaptation N/A
Enrolling by invitation NCT05876910 - Neural Mechanisms for Stopping Ongoing Speech Production N/A
Completed NCT04690166 - Validation of the Turkish Translation of the London Speech Evaluation Scale
Not yet recruiting NCT06234059 - Modulation of Sensory Acuity With Transcranial Magnetic Stimulation (TMS) N/A
Recruiting NCT05954520 - Effects of Nonlinear Signal Processing Algorithms on Speech Perception N/A