Speech Clinical Trial
Official title:
Behavioral and Neural Measures of Speech Motor Control
The purpose of this research study is to understand how the brain processes and controls speech in healthy people. The investigators are doing this research because it will help identify the mechanisms that allow people to perceive their own speech errors and to learn new speech sounds, which may be applied to people who have communication disorders. 15 participants will be enrolled into this part of the study and can expect to be on study for 3-4 visits of 2-4 hours each.
The overall study (Establishing the clinical utility of sensorimotor adaptation for speech rehabilitation) aims to understand how cognitive, perceptual, and motor processes are integrated in the control of speech movements. The investigators study how this complex skill is performed in healthy speakers to understand how this system functions, how this skill relates to the perception of speech, and what role different parts of the brain play in this process. Different studies look at how speech motor control is executed, maintained, and changed. Overall, the study will recruit 329 participants over the course of 5 years. Participants can expect to be on study for up to 3 weeks. The entire study is composed of 8 experiments and 6 interventions. The present record represents the experiments involving magnetoencephalographic (MEG) imaging, i.e. Experiment 5: Behavioral and neural responses to external alterations of speech variability. This paradigm modulates the perceived speech variability of participants through three different altered auditory feedback sessions: an inward-pushing feedback perturbation that decreases perceived variability by playing back participants' speech closer to the center of their vowel distributions, an outward-pushing feedback perturbation that increases perceived variability by playing back participants' speech farther from the center of their vowel distributions, and a normal feedback condition in which speech feedback is played back without perturbation. Participants will complete this paradigm during MEG imaging, which will noninvasively measure auditory cortical activity evoked during speech production and playback. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT06053190 -
Effects of Clear Speech on Listening Effort and Memory in Sentence Processing
|
N/A | |
Completed |
NCT04547569 -
Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning
|
N/A | |
Recruiting |
NCT05634356 -
Social Influences on Sensorimotor Integration of Speech Production and Perception During Early Vocal Learning
|
N/A | |
Completed |
NCT05635929 -
Oral Mucositis and Quality of Life With a Mucosa Topical Composition in Head & Neck Cancer Patients.
|
N/A | |
Recruiting |
NCT03504514 -
Evaluation of the Effect of a Speech Detection Tool on the Improvement of Phonation in Neuromuscular Patients Dependent on Mechanical Ventilation
|
N/A | |
Completed |
NCT05723575 -
Modulation of Sensory Acuity With Transcranial Magnetic Stimulation (TMS)
|
N/A | |
Completed |
NCT04010500 -
Speech Performance of Rugby Players When Using Different Types of Mouthguard
|
N/A | |
Completed |
NCT05256095 -
Thinking in Speech for Children With Autism
|
N/A | |
Not yet recruiting |
NCT06467305 -
Speech Motor Learning and Retention (Aim 1)
|
N/A | |
Not yet recruiting |
NCT06467292 -
Speech Motor Learning and Retention (Master Protocol)
|
N/A | |
Recruiting |
NCT02753192 -
Dysarthria in Parkinson's Disease: Lusophony vs. Francophony Comparison
|
N/A | |
Active, not recruiting |
NCT04273672 -
Speech, Linguistic and Acoustic Markers in Parkinson's Disease
|
||
Recruiting |
NCT06164717 -
Behavioral and Neural Characteristics of Adaptive Speech Motor Control
|
N/A | |
Completed |
NCT03008174 -
Early Speech With One-Way Speaking Valve in Tracheostomy Patients
|
N/A | |
Recruiting |
NCT06168695 -
Impact of Anterior Cross Bite Treatment on Children's Speech Performance
|
N/A | |
Recruiting |
NCT06233513 -
Vowel Space Expansion Sensorimotor Adaptation
|
N/A | |
Enrolling by invitation |
NCT05876910 -
Neural Mechanisms for Stopping Ongoing Speech Production
|
N/A | |
Completed |
NCT04690166 -
Validation of the Turkish Translation of the London Speech Evaluation Scale
|
||
Not yet recruiting |
NCT06234059 -
Modulation of Sensory Acuity With Transcranial Magnetic Stimulation (TMS)
|
N/A | |
Recruiting |
NCT05954520 -
Effects of Nonlinear Signal Processing Algorithms on Speech Perception
|
N/A |