Speech Disorders Clinical Trial
— EPG&SPTOfficial title:
Apraxia of Speech: A Comparison of EPG Treatment & Sound Production Treatment
NCT number | NCT02554513 |
Other study ID # | C2068-P |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | November 2, 2015 |
Est. completion date | June 28, 2019 |
Verified date | October 2021 |
Source | VA Office of Research and Development |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of the proposed research is to examine the effects of two treatment approaches on speech production involving speakers with chronic apraxia of speech (AOS) and aphasia. The planned investigation is designed to examine the acquisition, maintenance and generalization effects of each treatment. One approach, electropalatography (EPG) uses visual biofeedback in conjunction with articulatory-kinematic treatment and the other approach, sound production treatment (SPT) is one of the most systematically studied articulatory-kinematic treatments for AOS.
Status | Completed |
Enrollment | 6 |
Est. completion date | June 28, 2019 |
Est. primary completion date | February 1, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 21 Years to 80 Years |
Eligibility | Inclusion Criteria: - Veterans or non Veterans with apraxia of speech who reside in the Salt Lake City region (commutable), - 6 months or more post stroke or other focal brain injury, no other neurological conditions - native English speakers, hearing adequate for experimental task (e.g., pass puretone screening at 35dB at 500, 1K, 2K Hz or adequate aided hearing) - non linguistic cognition within normal limits Exclusion Criteria: - less than 6 months post stroke - insufficient hearing, insufficient non linguistic cognitive skills - neurological conditions other than stroke - unable to attend treatment in the Salt Lake City vicinity |
Country | Name | City | State |
---|---|---|---|
United States | VA Salt Lake City Health Care System, Salt Lake City, UT | Salt Lake City | Utah |
Lead Sponsor | Collaborator |
---|---|
VA Office of Research and Development |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Speech Production: Percent Change in Treated Items Immediately Post Treatment | Change in accuracy of articulation of treated items measured by percent increase in accuracy above the highest baseline measurement; production of words designated for treatment was measured repeatedly in non-treatment probes prior to treatment, throughout all study phases and immediately post treatment with percent accuracy calculated for each probe (0% to 100% correct). The highest percentage accuracy achieved in baseline probes was subtracted from the percentage accuracy achieved at the conclusion of treatment to obtain change in accuracy value - this reflects change from maximum correct performance in baseline (baseline). e.g., if in baseline probes, performance ranged from 10% to 30% accuracy and at post treatment performance was 90% accuracy, the change value would be 60% (90% minus 30%). A greater value indicates greater change in articulation/production of words. Change could be positive (improved articulation) or negative (poorer articulation) | Baseline vs. Immediately Post Treatment (7 week treatment period) | |
Secondary | Speech Production: Percent Change in Untreated Items (Related Items) Immediately Post Treatment | Change in articulatory accuracy of untreated items, but related items as measured by percent increase in accuracy above the highest baseline measurement; production of words designated for non-treatment was measured repeatedly in non-treatment probes prior to treatment, throughout all study phases and immediately post treatment with percent accuracy calculated for each probe (0% to 100% correct). The highest percentage accuracy achieved in baseline probes was subtracted from the percentage accuracy achieved at the conclusion of treatment to obtain change in accuracy value - this reflects change from maximum correct performance in baseline. e.g., if in baseline probes, performance ranged from 10% to 30% accuracy and at post treatment performance was 90% accuracy, the change value would be 60% (90% minus 30%). A greater change value indicates greater change in articulation/production of words. Change could be positive (improved articulation) or negative (poorer articulation) | Baseline vs. Immediately Post Treatment (7 week treatment period) | |
Secondary | Speech Production: Percent Change for Treated Items After the Completion of Treatment | Change in articulatory accuracy of treated items as measured by percent increase in accuracy above the highest baseline measurement; production of words designated for treatment was measured repeatedly in non-treatment probes prior to treatment, throughout all study phases, and at 7 weeks immediately after each treatment with percent accuracy calculated for each probe (0% to 100% correct). The highest percentage accuracy achieved in baseline probes was subtracted from the percentage accuracy achieved at 7 weeks immediately after the conclusion of each treatment to obtain change in accuracy value - this reflects change from maximum correct performance in baseline (pre-treatment). e.g., if in baseline probes, performance ranged from 10% to 30% accuracy and at post treatment performance was 90% accuracy, the change value would be 60% (90% minus 30%). A greater change value indicates greater change in articulation/production of words. | Baseline vs. 7 weeks post treatment [measured immediately after the completion of each treatment] | |
Secondary | Functional Communication Skills: T-Score | Measurement of functional every day communication skills using the Aphasia Communication Outcome Measure (ACOM) with a T-score computed at each administration which was at baseline and then 10 weeks after the completion of all treatment. This outcome measure was only completed at baseline and at the completion on all treatment [not measured after the completion of each treatment]. The rating scale for functional communication skills was completed by the patient (or a spouse if patient's auditory comprehension was significantly impaired) (T-Scores range from 0 to 100; Higher T-scores indicate greater functional communication skills) | Baseline vs. 10 weeks after the completion of all treatment [measured at pre-treatment and post-treatment; conclusion of all treatment] | |
Secondary | Speech Intelligibility: Percentage | Measurement of speech intelligibility for a set of fifty words (non-treatment words) from the Assessment of Speech Intelligibility of Dysarthric Speech as judge by an unfamiliar listener that was measured at baseline and then at 10 weeks post all treatment with a percentage of speech intelligibility (0% to 100% intelligible).This measurement was only conducted at pre-treatment and at the conclusion of all treatment [not measured after each treatment]. | Baseline vs. 10 weeks post all treatment [measured at pre-treatment and post-treatment; conclusion of all treatment] |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT02909088 -
Efficacy and Tolerability of Ecopipam in Adults With Childhood Onset Fluency Disorder (Stuttering).
|
Phase 2/Phase 3 | |
Recruiting |
NCT05695131 -
Clinical Feasibility & Validation of the Virtual Reality GlenxRose Speech-Language Therapies
|
N/A | |
Recruiting |
NCT04117360 -
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
|
||
Completed |
NCT02490826 -
Table to Tablet (T2T): A Novel Intervention Framework for Children With Speech Sound Disorders
|
N/A | |
Completed |
NCT02288598 -
Enhancing Speech Fluency With Non-invasive Brain Stimulation in Developmental Stuttering
|
N/A | |
Not yet recruiting |
NCT04528147 -
Yi Jin Jing Tiger Roaring Speech Rehabilitation With Real-Time Feedback Technique for PD
|
N/A | |
Recruiting |
NCT05876247 -
Articulatory Adaptation Following Oral Cancer Treatment
|
||
Recruiting |
NCT05489965 -
Gender Disparities in Voice Outcomes After Tracheoesophageal Puncture in Total Laryngectomy Patients (UC Davis)
|
||
Completed |
NCT02752425 -
Visual Feedback of Tongue by Ultrasound Echography for Speech Trouble Rehabilitation
|
N/A | |
Recruiting |
NCT06443073 -
The Mere-measurement Effect of Patient-reported Outcomes
|
N/A | |
Recruiting |
NCT05741853 -
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
|
N/A | |
Completed |
NCT04026581 -
Real World Testing of a Brain-Computer Interface
|
||
Active, not recruiting |
NCT04937452 -
Dopaminergic Therapy for Frontotemporal Dementia Patients
|
Phase 2 | |
Completed |
NCT02416856 -
Brain Connectivity Supporting Language Recovery in Aphasia
|
||
Completed |
NCT01180309 -
Lingual Frenum and Articulation of Phonemes
|
N/A | |
Completed |
NCT03663972 -
Age-related Correlates of Treatment for Late-acquired Sounds
|
N/A | |
Not yet recruiting |
NCT04323085 -
Speech-in-Noise Treatments for Hypophonia in Parkinson's Disease
|
Phase 2 | |
Completed |
NCT00125242 -
Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis
|
N/A | |
Completed |
NCT04966689 -
The Effect of Combined Speech and Music-therapy on the Speech Characteristics of People With Parkinson's Disease (PD)
|
N/A | |
Completed |
NCT04009811 -
A New Membrane Obturator Prothesis Concept for Soft Palate Defects
|
N/A |