Effects of Stress on Exposure Therapy

Status Completed

Clinical Trial Summary

This study investigates whether stress can augment exposure therapy outcome in patients with specific phobia (spider phobia).

Clinical Trial Description

Stress has been shown to modulate fear extinction. The present study is aimed at investigating whether stress (administered prior to exposure with the socially evaluated cold pressor test) augments exposure therapy outcome in patients with specific phobia (spider phobia). Furthermore, the effects of stress on the generalization of exposure-induced symptom reduction towards untreated fear stimuli (i.e. cockroaches) will be explored.

Participants are randomly assigned to the cold or warm water condition of the socially evaluated cold pressor test (SECPT; Schwabe et al., 2008). Thereafter, participants of both conditions receive 45 minutes of in-vivo exposure to spiders. The effects of stress on exposure-based anxiety reductions toward spiders (treated fear stimulus) and cockroaches (untreated fear stimulus to assess generalization of treatment outcome) are assessed on the behavioral, subjective and physiological level at pretreatment, posttreatment (24 hours after exposure) and follow-up (4 weeks after exposure). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03505437
Study type	Interventional
Source	Ruhr University of Bochum
Contact
Status	Completed
Phase	N/A
Start date	April 20, 2018
Completion date	August 30, 2019

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