Clinical Trials Logo
  1. Home
  2. Specific Phobia
  3. NCT00872716

Quetiapine in Specific Phobia — QUISS  

Specific Phobia Clinical Trial

Official title:
Anxiolytic Effects of Single-dose Quetiapine XR Administration on Clinical Symptoms and Amygdala Activation During Exposure in Patients With Simple Phobia

Clinical Trial Summary

The study hypothesis is that quetiapine XR has anxiolytic properties. The study aims to investigate the putative anxiolytic properties of quetiapine XR in patients with anxiety disorders. Therefore, in a proof-of-concept design patients with simple phobia will be selected to investigate specific anxiolytic and antipanic activity during acute anxiety. Moreover, in a combined fMRI/visual stimulus presentation paradigm activity of fear-network associated brain structures such as the amygdala will be investigated under treatment with quetiapine XR or placebo. Additionally, genetic factors potentially mediating anxiolytic properties of quetiapine will be studied.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00872716
Study type Interventional
Source University Hospital Muenster
Contact
Status Completed
Phase Phase 2
Start date April 2009
Completion date March 2011
View Details
See also
  Status Clinical Trial Phase
Terminated NCT04594525 - Maternal Telemental Health Interventions in Response to Covid-19* N/A
Completed NCT02306356 - Internet-delivered Treatment for Children With Anxiety Disorders in a Rural Area; an Open Trial in a Clinical Setting N/A
Completed NCT03233113 - The Effects of Safety Seeking Behaviors During Exposure Therapy for Adults With Spider Phobia N/A
Completed NCT04504773 - Using Immersive Virtual Reality to Treat Pediatric Anxiety N/A
Completed NCT05300061 - Values Interventions for Increasing Engagement With What is Feared in Individuals With Specific Phobias N/A
Completed NCT03208400 - Virtual Reality Exposure in Spider Phobia N/A
Completed NCT03688373 - Facing Fears in Big or Smalls Steps? N/A
Completed NCT03688360 - Facing Fears In-session or Out-session? N/A
Recruiting NCT02305537 - Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment N/A
Terminated NCT01979263 - Attention Bias Modification Treatment for Anxious Youth N/A
Terminated NCT03764644 - Web-based Attention Bias Modification Treatment for Childhood Anxiety Disorders N/A
Not yet recruiting NCT02972112 - Ultrashort Cognitive Behavioral Intervention for Tokophobia- A Prospective Randomized Single Blinded Controlled Trial N/A
Completed NCT02554838 - How to Act on the Mobility Restriction Linked to Senior's Phobia of Falling N/A
Completed NCT01491880 - Treatment Study for Rural Latino Youth With Anxiety Phase 1/Phase 2
Completed NCT01947647 - Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders N/A
Recruiting NCT04563390 - Effectiveness of a Projection-based Augmented Reality Exposure System in Treating Cockroach Phobia. N/A
Completed NCT05284435 - Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASD N/A
Completed NCT03105024 - Self-efficacy Enhancement and Exposure Therapy N/A
Completed NCT01923896 - D-cycloserine and Treatment of Feeding Disorders Phase 1/Phase 2
Recruiting NCT03917550 - RECOVERY: A Transdiagnostic Intervention for Anxiety and Depression N/A