Effect of Nebulized Lidocaine on Postoperative Sore Throat

Status Terminated

Clinical Trial Summary

The purpose of this study is to test the hypothesis that use of preoperative nebulized lidocaine is reduced the incidence of postoperative sore throat after endotracheal intubation.

Clinical Trial Description

Adult patients undergoing video-assisted thoracic surgery (VATS) requiring double lumen tube (DLT) endotracheal intubation for one-lung ventilation (OLV) were enrolled in the study. Patients were randomized by means of computer-generated order randomization into two groups: Group C (those who received a saline solution as placebo delivered by nebulization) and Group L (those who received lidocaine delivered by nebulization).

At 1, 6 and 24 h after tracheal extubation, an observer blinded to treatments evaluated the patients in terms of sore throat and hoarseness. In addition, Patients' satisfaction, intraoperative and postoperative opioid and analgesics consumption and complaints such as dysphagia, nausea and vomiting were recorded. Hemodynamic variables such as blood pressure and heart rate were also recorded. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03779516
Study type	Interventional
Source	Antalya Training and Research Hospital
Contact
Status	Terminated
Phase	N/A
Start date	December 19, 2018
Completion date	July 15, 2019

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