Sore Throat Clinical Trial
Official title:
Comparison of the Efficacy of Intravenous Dexketoprofen and Paracetamol in the Treatment of Pain in Patients Presenting to the Emergency Department With Sore Throat: A Double-Blinded, Randomized, Controlled Trial
Verified date | December 2018 |
Source | Pamukkale University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Currently, paracetamol and nonsteroidal antiinflammatory drugs are widely used by emergency physicians in Turkey for the treatment of sore throat. The objective of the study is compare the efficacy of intravenous dexketoprofen and paracetamol in the treatment of the pain in patients presenting to the emergency department with sore throat
Status | Completed |
Enrollment | 200 |
Est. completion date | July 30, 2018 |
Est. primary completion date | July 30, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Patients with sore throat less than three days - Patients with at least one of the following: - According to the throat pain scale, patients with moderate-severe pain, - At least 1 upper respiratory tract infection (URTI) symptom according URTI questionare, - Objective findings of pharyngeal inflammation (Tonsillopharyngitis evaluation score =5), - 60 mm or more according to the sore throat sensitivity scale (STSS), - 50 mm and above according to difficulty swallowing scale (DSS), - 33 mm and above according to the swollen throat scale (SwoTS) Exclusion Criteria: - Patients use analgesic last 12 hours - Patients with severe liver, kidney,pulmonary and cardiac heart failure - To be Pregnancy and breast-feeding Patients of childbearing age who are not using a birth control method - Patients with an allergy trait (paracetamol and dexketoprofen) Illiterates - Patients with vision problems - Patients use antibiotics last 24 hours - Patients use kinolons last 7 days - Patienst use lozange,throat spray or menthol containing products last 4 hours - Hemodynamically unstable patients,Patients with renal transplantation - Patients with glucose 6 phosphate dehydrogenase (G6PD) deficiency - Patients with non-controlled hypertension - Patients with a history of cerebrovascular disease - Patients with Wolff-Parkinson-White syndrome or accompanying arrhythmias associated with conductive stimulus delivery in the heart |
Country | Name | City | State |
---|---|---|---|
Turkey | Pamukkale University | Denizli |
Lead Sponsor | Collaborator |
---|---|
Pamukkale University |
Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Decreament of the pain | Comparison of the change of sore thorat pain VAS (visual analog scale) and Sore throat relief scale score between the two groups. - (First group Paracetamol and Second Dexketoprofen) | Baseline and 120 minutes | |
Secondary | Symptom frequency | Detection of upper respiratory tract infections symptoms frequency by using upper respiratory tract infections questionnaire | Baseline and 120 minutes |
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